CNS pathology II Flashcards Preview

Jason's MD2 Surgery Rotation > CNS pathology II > Flashcards

Flashcards in CNS pathology II Deck (18):
1

GFAP stain is for what?

stains intermediate fibres of glial cells, means it's more

2

glioblastoma multiforme rx usu.?

temozolomide
radiation

3

common brain tumours

gliomas
meningiomas
acoustic nerve schwannomas
pituitary adenomas

4

where do most tumours occur in kids?

infratentorial or spinal cord

5

NF-1 risk of what tumour?

optic nerve pilocytic astrocytoma

6

rosenthal fibres found in what tumours?

pilocytic astrocytomas

7

types of gliomas

astrocytoma
ependymoma
oligodendroglioma

8

1p19q codeletion in gliomas means?

good survival

9

meningiomas come from? who gets them usually? risk factors?

near dura
middle aged women
NF-2

10

tumours that met to brain are?

lung
breast
renal cell
colorectum
melanoma

11

features of brain abscess

central necrosis, neutrophils
layers of inflamed granulation tissue

12

4 ways you get brain abscess?

direct extension: sinusitis, otitis media, dental abscess
haematogenous - lung, I drug, infective endocarditis
trauma
unknown

13

epidural abscess is usu. what organism?

staph aureus

14

parkinson's has 2 findings

1. loss of pigmented dopaminergic neurons in substantia niagra
2. lewy bodies

15

environmental factors in parkinson's?

pesticides
quarry's

16

toxins for parkinson's?

MPTP and manganese

17

primary angiitis is?

lymphocytes within the vessel wall, vasculitis

18

features of a high grade brain tumour?

highly dense and cellular and mitotic

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