Common Skin Conditions - Skin Fungal Inf Flashcards Preview

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Flashcards in Common Skin Conditions - Skin Fungal Inf Deck (38):
0

What's athletes foot (tinea pedis)?

Fungal infection caused commonly by TRICHOPHYTON RUBRUM

1

What's Jock itch (Tinea cruris)

Affects the genitals, inner thighs and buttocks

2

What's ringworm (tinea corporis)?

Not a worm, but skin infection

Looks like circular, red, flat sores

3

What's Tinea capitis?

Ringworm on the scalp

4

In what grp of people is cutaneous (skin) candida infection most common?

Obese people bcuz they have more skin with folds

5

List drugs used for skin fungal tx?

Terbinafine and butenafine (highly effective)

Clotrimazole

6

What's the brand name of Terbinafine? How does it come?

Lamisil AT cream and soln

7

List non-pharmacologic ways to treat fungal skin inf?

Reduce moisture to infected area

If foot ing, don't walk barefoot (to avoid spreading it)

Wear scandals in public showers

8

What's important for diagnosis of Onycomycosis (Tinea Unguium)?

20% potassium hydroxide (KOH) smear is essential for diagnosis as other conditions are similar

9

List agents used for Onycomycosis (Tinea Unguium)

Itraconazole (Sporanox)

Terbinafine (Lamisil, Terbinex)

Ciclopirox (Penlac, Loprox)

10

What's the difference btw Lamisil and Lamisil AT?

Lamisil is oral Terbinafine

Lamisil AT is topical Terbinafine (used for fungal skin inf)

11

What's the brand name of Itraconazole?

Sporanox

12

What's the black box warning associated with Itraconazole (Sporanox)?

Avoid use in HF

Req gastric acid for absorption

Can't use strong acid suppressing agents concurrently

13

SE of systemic terbinafine (Lamisil, Terbinex)?

Headache (primarily)

Rash

Nausea

Risk of hepatotoxicity

14

What should be monitored using systemic antifungals? (Itraconazole - Sporanox; Terbinafine - Lamisil, Terbinex; Ciclopirix - Penlac, Loprox)?

Liver enzymes/ sx of liver toxicity

15

What's the sx of vaginal fungal candida (yeast) infection?

Itching with soreness and pain (burning) during urination or sex

16

What natural pdt is considered possibly effective in vaginal fungal candida (yeast) inf?

Lactobacillus or yoghurt with active cultures

17

What's used in mild-moderate, infrequent inf?

OTC, topical agents

Butoconazole
Clotrimazole
Miconazole (Monistat)
Terconazole
Tioconazole (Vagistat-1)

18

What's the duration of tx in mild-moderate, infrequent vaginal yeast inf?

1 or 3 day tx

19

What's used in complicated vaginal yeast infections and in pregnancy?

Fluconazole (Diflucan)

7-10 days tx

20

What should be avoided with use of OTC antifungals (for vagina yeast inf)?

Avoid sexual intercourse (creams and suppositories are oil-based and
can weaker latex condoms and diaphragm)

Don't use tampons during tx

21

What's essential in Eczema (Atopic Dermatitis) tx?

Hydration is essential

Use moisturizers (petrolatum, lanolin, pdts such as Aquaphor, Eucerin, Keri or store brands)

22

List agents used in Eczema (Atopic Dermatitis)

Topical corticosteroids

Antihistamines (for itching)

Immune-suppressant calcineurin inhibitors (if topical steroids + hydration are not adequate)

23

Whats the 1st line of tx for Eczema (Atopic Dermatitis)?

Topical steroids

24

What's used as last-line in Eczema (Atopic Dermatitis)?

Tacrolimus (Protopic)

Pimecrolimus (Elidel)

25

How do u use Tacrolimus (Protopic) and Pimecrolimus (Elidel)?

Apply thin layer only to affected skin areas, twice a day

Use smallest amt needed to control sx

Wash hands after application

26

Why is Lindane (Kwell) no longer used for lice tx?

Bcuz of neurotoxicity

27

List agents used in lice

Pyrethrins (permethrin) OTC drug of choice

Malathion lotion 0.5% (Ovide)

Benzyl alcohol lotion (Ulesfia 5% lotion)

Lindane shampoo 1%

28

Which lice agent kills live lice but not nits?

Benzyl alcohol lotion (Ulesfia 5% lotion)

29

What's the OTC drug of choice for lice?

Permethrin (Pyrethrins)

30

What can be done in addition to OTC lice tx?

Remove live lice and nit (use 1-inch segments and lice comb)

Without removing live lice and nit, OTC pdt won't work

31

When is tx of genital warts not req?

When there's no sx

32

What agent is used in genital warts?

Imiquimod cream

33

How to use imiquimod cream?

Apply to entire tx area b4 bedtime and rub in unit cream is no longer visible

Use only 1 packet per application

Wash off after 8 hrs

Apply 3x/wk until clearance or 16 wks duration

34

What's the primary tx for skin irritation?

Topical steroids

35

What strength of topical steroids is OTC?

Hydrocortisone (HC) OTC, 0.5%, 1%

All other topical strength are rx

36

Rank different dosage forms from highest potency to weakest potency? (Creams, lotions, ointment, sprays, gel)

Ointment > creams > lotions > solns > gels > spray

37

What's used to represent pea-sized amt?

Finger-tip unit

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