Flashcards in Weight Loss Deck (28):
What weight loss produces clinically meaningful health benefits?
Wt loss of 3-5%
What's the result of a 500 kcal decrease per day?
1 pound weight lost per week (3,500 kcal/ pound)
What's the amt of regular physical activity req to lose weight?
When's Bariatric surgery recommended?
Adults with BMI >= 40
BMI >= 35 + an obesity-related comorbid condition
List OTC weight loss drugs?
Caffeine- containing pdts
In what grp of pt is rx weight loss pdts not recommended?
Those with small weight to lose
Those who are not obese or overweight with at least 1 weight-related co-morbidity e.g. DM, HTN
Howz rx weight loss pdts used?
In addition to a dietary plan + increased physical activity, per FDA
What's the "7-yr rule" of new meds?
Don't recommended new agents until they have been out for awhile and used in millions -- not including ur pts, friends and family-- in order to get a more complete understanding of ADRs
MOA of Phentermine?
Sympathomimetic, with effects similar to amphetamines, causing increase in NE
Moa of Topiramate?
Effects due to decreased appetite and safety, possibly by enhancing GABA, blocking glutamate receptors and/or weak inhibition of carbonic Anhydrase
Brand name of Phentermine + Topiramate ext-release capsule?
SEs of Qsymia?
Reduced serum bicarbonate
Upper respiratory tract inf
Agents under Serotonin 5-HT2c receptor agonist?
List short-term appetite suppressants
Phentermine (Adipex-P, Suprenza-ODT)
Long-term lipase inhibitor agent?
Orlistat (Xenical) Rx
Orlistate (Alli) OTC
How should both formulations be used?
What should be taken with Orlistat?
MTVE A, D, E,K & Beta carotene at bedtime
Separate by 2+ hrs
What's 1 of the most common problem of Bariatric surgery?
Calcium citrate is preferred (cuz of non-acid dependent absorption)
What causes anemia post-Bariatric surgery?
Vit. B12 + Iron deficiency.
Both req supplementation
Should iron and Ca be taken together?
They should be separated
Why may some req lifelong supplementation of fat-soluble vits A, D, E, K?
Due to fat malabsorption
How do u take meds up to 2-months post-surgery?
Meds should be Crushed or in liquid or transdermal form for up to 2-months post-surgery
Why do post-Bariatric surgery req Ursodiol (Actigall, Urso 250, Urso Forte)?
Due to risk of gallstone formation due to rapid weight loss
These drugs dissolve gallstones
Which drugs should be avoided post-Bariatric surgery? Why?
NSAIDs + Bisphosphonates
They are GI irritants
What's dumping syndrome?
Rapid gastric emptying, which occurs when in digested food moves rapidly into the small intestines
Common sx of dumping syndrome?
Methods to avoid dumping syndrome?
Eat smaller meals
Use fluids btw meals only
Avoid alcohol + acidic food
Don't lie down after eating