Weight Loss Flashcards Preview

NAPLEX > Weight Loss > Flashcards

Flashcards in Weight Loss Deck (28):
0

What weight loss produces clinically meaningful health benefits?

Wt loss of 3-5%

1

What's the result of a 500 kcal decrease per day?

1 pound weight lost per week (3,500 kcal/ pound)

2

What's the amt of regular physical activity req to lose weight?

200-300 min/wk

3

When's Bariatric surgery recommended?

Adults with BMI >= 40

Or

BMI >= 35 + an obesity-related comorbid condition

4

List OTC weight loss drugs?

Fastin

Caffeine- containing pdts

Alli

5

In what grp of pt is rx weight loss pdts not recommended?

Those with small weight to lose

Those who are not obese or overweight with at least 1 weight-related co-morbidity e.g. DM, HTN

6

Howz rx weight loss pdts used?

In addition to a dietary plan + increased physical activity, per FDA

7

What's the "7-yr rule" of new meds?

Don't recommended new agents until they have been out for awhile and used in millions -- not including ur pts, friends and family-- in order to get a more complete understanding of ADRs

8

MOA of Phentermine?

Sympathomimetic, with effects similar to amphetamines, causing increase in NE

9

Moa of Topiramate?

Effects due to decreased appetite and safety, possibly by enhancing GABA, blocking glutamate receptors and/or weak inhibition of carbonic Anhydrase

10

Brand name of Phentermine + Topiramate ext-release capsule?

Qsymia

11

SEs of Qsymia?

Dizziness

HA

Cognitive impairment

Constipation

Dry mouth

Insomnia

Paresthesias

Reduced serum bicarbonate

Upper respiratory tract inf

Pharyngitis

12

Agents under Serotonin 5-HT2c receptor agonist?

Lorcaserin (Belviq)

13

List short-term appetite suppressants

Phentermine (Adipex-P, Suprenza-ODT)

Diethylpropion (Tenuate)

14

Long-term lipase inhibitor agent?

Orlistat (Xenical) Rx

Orlistate (Alli) OTC

15

How should both formulations be used?

Low-fat diet

16

What should be taken with Orlistat?

MTVE A, D, E,K & Beta carotene at bedtime

Or

Separate by 2+ hrs

17

What's 1 of the most common problem of Bariatric surgery?

Calcium deficiency

Calcium citrate is preferred (cuz of non-acid dependent absorption)

18

What causes anemia post-Bariatric surgery?

Vit. B12 + Iron deficiency.

Both req supplementation

19

Should iron and Ca be taken together?

No!

They should be separated

20

Why may some req lifelong supplementation of fat-soluble vits A, D, E, K?

Due to fat malabsorption

21

How do u take meds up to 2-months post-surgery?

Meds should be Crushed or in liquid or transdermal form for up to 2-months post-surgery

22

Why do post-Bariatric surgery req Ursodiol (Actigall, Urso 250, Urso Forte)?

Due to risk of gallstone formation due to rapid weight loss

These drugs dissolve gallstones

23

Which drugs should be avoided post-Bariatric surgery? Why?

NSAIDs + Bisphosphonates

They are GI irritants

24

What's dumping syndrome?

Rapid gastric emptying, which occurs when in digested food moves rapidly into the small intestines

25

Common sx of dumping syndrome?

Abdominal cramps

Nausea

Diarrhea

26

Methods to avoid dumping syndrome?

Eat smaller meals

Use fluids btw meals only

Reduce carbs

Increase fiber

Avoid alcohol + acidic food

Don't lie down after eating

27

What rx drugs are used for dumping?

Acarbose (Precose)

Octreotide (Sandostatin)

Decks in NAPLEX Class (73):