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Flashcards in Migraine Deck (25):
0

What's Triptans?

5HT1 Serotonin-receptor agonists that cause vasodilation of cranial blood vessels

1

List common migraine triggers

Hormonal changes in women

Foods

Stress

Sensory stimuli

Changes in wake-sleep pattern

Changes in the environment

2

What's used for acute tx?

Triptans

NSAIDs or Excedrin Migraine

3

List triptans used in migraine

Naratriptan (Amerge)

Almotriptan (Axert)

Frovatriptan (Frova)

Sumatriptan (Imitrex, Alsuma)

Eletriptan (Relpax)

Rizatriptan (Maxalt, Maxalt-MLT)

Zolmitriptan (Zomig, Zomig-ZMT disint tabs)

4

Brand name of Sumatriptan? (Needleless sumatriptan injection)

Imitrex

Alsuma

5

Brand name of Sumatriptan? (SC injection)

Imitrex STATdose SC dose

6

Brand name of Sumatriptan? (Nasal spray)

Imitrex nasal spray

7

Brand name of Rizatriptan?

Maxalt

Maxalt-MLT

8

Brand name of Eletriptan?

Relpax

9

Ses of Triptans?

Triptan sensations, includes pressure in the chest or heaviness or pressure in the neck region and usually dissipate after admin

10

Which triptans has a nasal and SC inj formulation?

Sumatriptan

11

Long-acting (but slower onset) triptans?

Frovatriptan (Frova)

12

Shorter half-life (duration) but quick onset triptans?

Almotriptan (Axert)

Eletriptan (Replax)

Rizatriptan (Maxalt)

Sumatriptan (Imitrex, Alsuma)

Zolmitriptan

13

Which triptans are CI with MAO-I use?

Imitrex (Sumatriptan)

Maxalt (Rizatriptan)

Zomig (Zolmitriptan)

14

When should migraine prophylaxis be considered?

Migraine tx > 2 x a wk

Or

Migraine decreases quality of life

15

What's 1st line agents for migraine prophylaxis?

Beta-blockers e.g.
Propranolol (Inderal)
Timolol (Blocadren)
Metoprolol (Lopressor, Toprol XL)

Valproate
Topiramate (Topamax)

16

What's 2nd line agents for migraine prophylaxis?

Other beta-blockers

ACE-I

Antidepressant

Natural pdts

OCPs (for premenstrual migraine)

Botulinum toxin type A (chronic migraine only...last >= 15 days/month)

17

Ses of valproate/Divalproex?

Liver toxicity

Pancreatitis

Weight gain

Teratogenicity

Thrombocytopenia

18

SEs of Topiramte?

Weight loss

19

Whens Botulinum toxin type A used in migraine?

For chronic migraine only...last >= 15 days/month

20

Do u prime Zomig and Imitrex spray before use?

NO!!!!!!!!

21

Where do u admin Imitrex-STAT dose?

SC, upper outside arm

22

Which med is approved to treat pre-menstrual migraine + aura in women?

Nor-QD

Nora-Be

Camila

23

What does Fiorinal contain? Class in CS?

Aspirin + Butalbital + Caffeine

C-III

24

How often do u repeat the dose of Sumatriptan? PO, Nasal spray, SC injection

PO & Nasal spray - can repeat after 2 hrs

SC - after 1 hr

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