Concepts in Haematology Flashcards Preview

3 Haematology > Concepts in Haematology > Flashcards

Flashcards in Concepts in Haematology Deck (12)
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1
Q

why might the cell count be low?

A

inc destruction
reduced production
redistribution

2
Q

why might the cell count be high?

A

inc production in response to stimulus
inc production with no stimulus (malignancy)
redistribution

3
Q

steroids cause an increase in what cell? why is this

A

neutrophils

cause redistribution of neutrophils to a more easily sampled place (production HASNT gone up)

4
Q

-cytosis and -philia means an excess/lack

A

excess

5
Q

-penia means an excess/lack

A

lack

6
Q

difference between reticulocytes and RBCs

A

have RNA but no nucleus (precursors to RBCs)

RBCs dont have RNA

7
Q

what 2 substances catalyse biochemical steps to cell division

A

B12

folic acid

8
Q

what cells detect hypoxia? where do they do this?

A

fibroblasts

peritubular capillaries and PCT of kidney

9
Q

what does inc erythropoetin cause and why?

A

erythroid hyperplasia

stimulates production of red cell precursors eg reticulocytes

10
Q

iron absorption occurs where?

A

duodenum and proximal SI

11
Q

name the raw materials for RBC production

A

iron stores
globin synthesis
haem

12
Q

you get jaundice from the inc bilirubin in chronic hypoxia T or F

A

F, system has time to adapt so wont