Flashcards in Connective Tissue Deck (64)
Name the germ layers in the embryo
Endoderm, Mesoderm, Ectoderm
What does mesenchymal tissue do?
Mesenchymal tissue creaes adult connective tissue like blood, supportive and proper tissues
What is adipose tissue dervied from?
The mesoderm, this separates brown and white fat
Where is connective tissue derived from?
Mainly the mesoderm
What is the main function of connective tissue?
What functions does connective tissue provide?
Structural support, cushioning, delivery and storage of nutrients, cell repair
What is a fixed (resident) cell?
A cell that does not move from the tissue in which it originates
What is a non-resident cell?
A cell that is transient between tissues
What is connective tissue made of?
Cells (fixed or mobile), fibers, and ground substance
How does connective tissue differ from epithelial cells?
Connective tissue does not have a basement membrane
Name fixed cells
Fibroblast, Macrophage, Mast cell, Percyte, Adipocyte, Mesenchymal cell
Name mobile cells
Macrophage, plasma cell, lymphocyte, polymorphonuclear cells (neutrophils), eosinophil, basophils
What does the bone marrow make?
multipotent stem cells that evolve in to immune cells (eosinophil, neutrophil, plasma, lymphocyte, macrophage, osteoclast, red blood cell)
What does the mesenchymal cell make?
embryonic connective tissues including osteoblasts, adipocytes, and fibrolbasts
Name typical peripheral blood cells
Erythrocyte, lymphocyte, neutrophil, eosinophil, basophil, monocyte, platelets
Describe a fibroblast
Produce collagen and elastin, oblong heterochromatic nucleus with no visible cytoplasm
What cell is a macrophage derived from?
What is the main function of macrophages?
Engulfing antigen and presenting the antigen for T cells. T cells are activated to either cytotoxic CD4 T cells or helper CD8 T cells
Where are dendritic cells found
Dendritic cells have tree-like structures and are found in the skin and epithelium.
What is the function of dendritic cells
Present antigen to stimulate B or T cells at lymph nodes. Dendritic cells have a euchromatic nuclei and large cytoplasm
Where are mast cells located
Connective tissue. Mast cells produce heparin and histamine
What is heparin
Describe mast cell
Red granulated cytoplasm with large, dark nucleus
Mast cells account for allergic responses and wound repair
What is a pericyte
Contractile cell located on the edge of vasculature. Dark nucleus with little cytoplasm
Describe the mononuclear phagocyte system
Bone marrow makes a pluripotential stem cell, which matures to a committed stem cell to monoblast to promonocyte to monocyte that is secreted to peripheral blood. Monocyte becomes macrophage
Describe a lymphocyte
Dark, round nucleus with no cytoplasm
Describe a plasma cell
A mixture of heterochromatin and euchromatin in the nucleus to give a spotted look, basophilic cytoplasm and large golgi apparatus
How are antibodies produced
B-cells digest the antigen and presents antigen on cell surface. B cell interacts with activated T cells, differentiates in to a plasma cell and begins producing antibodies
Name types of lymphocytes
CD4+ T cells, CD8 B cells, Helper T cells, Natural Killer T cells, regulatory T cells