Nerves Flashcards

1
Q

Where are ganglion located?

A

Outside CNS

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2
Q

What does the central nervous system consist of?

A

Brain and Spinal cord

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3
Q

What does the peripheral nervous system consist of?

A

Everything except brain and spinal cord

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4
Q

What is the cell body called?

A

Soma, perikaryon

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5
Q

What is Nissl substance and where is it located?

A

Clumps of rER located in the cell body and dendrites

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6
Q

Does the soma have a nucleolus?

A

Yes

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7
Q

What is the background of nervous tissue called?

A

Neutropil

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8
Q

Do dendrites conduct signals toward or away from the soma?

A

Toward

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9
Q

D axons conduct signals towards or away from soma?

A

Away

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10
Q

When do axons not transmit information away from the soma?

A

Pseudounipolar neurons

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11
Q

What cells produce myelin in the central nervous system? Peripheral?

A

Central: oligodendrocytes
Peripheral: Schwann cells

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12
Q

What are the 3 types of neuron shape?

A

Bipolar, pseudounipolar, multipolar

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13
Q

What are bipolar neurons used for?

A

Sight, hearing, smell

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14
Q

What are pseduounipolar nerves used for?

A

Regular sensory neurons

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15
Q

What are multipolar neurons used for?

A

Most motor neurons

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16
Q

Where can synapses occur?

A

Cell body, axons, dendrites

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17
Q

What is bodain classification of neurons?

A

Dendritic zone (area that is stimulated/inhibited)

Axonic zone (conducting part)

Telodendritic zone (terminal mods that allow for transfer of information at synapse)

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18
Q

What is the bodain classification of a bipolar neuron?

A

Dendritic zone: Dendrites

Axonic zone: Axon & cell body

Telodendritic zone: End of axon

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19
Q

What is the bodain classification of a pseduounipolar neuron?

A

Dendritic zone: on lower part of neuron

Axonic zone: Axon, cell body

Telodendritic zone: right above cell body

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20
Q

What is the bodain classification of a multipolar neuron?

A

Dendritic zone: Dendrites & cell body

Axonic zone: Axon

Telodedritic zone: End of axon

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21
Q

What are the neuroglial cells of the central nervous system?

A

Astrocytes, Microglia, Oligodendrocytes, Ependymal cells

22
Q

What are the glial cells of the peripheral nervous system?

A

Satellite cells (ganglionic gliocytes)

Schwann cells (neurolemmocytes)

23
Q

What is the purpose of neuroglial cells?

A

To provide support to the central nervous system because there is little CT

Form scars by proliferating astrocytes after injury

Nutrition, communication

24
Q

What is an astrocyte?

A

Largest neuroglial cell

Protoplasmic is found in grey matter

Fibrous is found in white matter (surround nodes of ranvier)

25
What is the purpose of astrocytes?
Recycle neurotransmitters, maintenance of synapses, maintain the blood-brain barrier, antigen-presenting
26
What diseases are astrocytes key in?
Alzheimers, ALS, Alexander's disease
27
Where are oligodendroglia located?
In the CNS In grey matter near perkarya to produce myelin In white matter to produce myelin
28
How many neurons can one oligodendrocyte envelop?
Several
29
What are ependymal cells?
Line cavity of brain and spinal cord Contribute to formation of Cerebrospinal fluid Stem cell properties (proliferate in response to injury, generate neuroblasts and astrocytes)
30
What are microglial cells?
Small and dense phagocytic cells
31
What is the bouton?
Expanded area of the axon that contributes the presynaptic membrane
32
Describe the synaptic cleft
Gap between neurons that contains fine filaments and electron dense material
33
What is the subsynaptic web?
Filamentous materials associated with the post synaptic membrane
34
What is the tripartite synapse?
Astrocytic processes at the synaptic cleft form connections with neuronal synapses and each other with gap junctions
35
Does neurogenesis occur?
Yes, throughout life. Neural stem cells have astrocytic and neuroepithelial potential Ependymal cells of the central canal are pluripotential
36
What is dedifferentiation?
Progenitor cells are mono or uni-potent. If a cell becomes bipotent it has dedifferentiated to a stem cell
37
What is transdifferentiation?
A cell becoming a cell type from a different embryonic lineage
38
Where is epineurium located?
Around entire nerve fiber
39
Where is perineurium located?
Around each fasicle
40
What are the perineural cells?
A sleeve-like layer of epithelioid cells immediately around fasicles
41
What is endoneurium?
Surrounds individual axons (along with myelin)
42
How many neurons can schwann cells envelop?
One, many schwann cells on one axon
43
Describe unmyelinated fibers
Several nerve fibers sit in simple clefts of schwann cells
44
What is the gap between schwann cells called?
Node of ranvier
45
What is each separate myelin segment referred to as?
Internode
46
Why don't myelin sheaths stain?
They're made of mostly lipids
47
Where are satellite cells located?
Surrounding the perikarya in the ganglion
48
What neuron types do not leave the CNS?
Interneuron, upper motor neuron
49
What are the 3 layers of connective tissue that surround the CNS?
``` dura mater (outer) arachnoid (inner) pia mater (inner) ```
50
What space is filled with CSF?
Subarachnoid space