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BIOSCI > Connective Tissue > Flashcards

Connective Tissue Flashcards

1
Q

Functions of CT

A

strengthens, binds, supports
transports- blood
Stored energy reserve- adipose/ fat

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2
Q

Describe where CT is and its characteristics

A 
Not found on body surface (blood cartilage)
Highly vascular (except for cartilage/ tendons)
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3
Q

What is the equation for CT

A

CT= ECM + Cells

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4
Q

Equation for ECM

A

ECM= GS + Fibers

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5
Q

Where are protein fibers made and what dictates the structure of the CT

A

Protein fibers are secreted by the ECM

structure of the ECM largely dictates the structure

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6
Q

Equation for GS

A

GS= h20+ proteins+ proteoglycans (sugars)

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7
Q

What form Proteoglycans

A

GAGs + core proteins= proteoglycans

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8
Q

GAG examples

A

Dermatan/Keratan/Chondroitin SULPHATE

or Hyaluronic acid

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9
Q

What do GAGS do

A

Trap water

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10
Q

Describe Hyaluronic Acid

A

Not sulphate/ covalently bonded
Binds cells together, Lubricates Joints and maintains shape of eyeballs
- Makes GS more liquid like
Produced by WBS, sperm and bacteria

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11
Q

Chrondrotin Sulphate location

A

cartilage, bone, skin/ Blood vessel

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12
Q

Keratan sulphate

A

bone/ cartilage/ cornea of eye

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13
Q

Dermatan sulphate

A

skin, tendons Blood vessels and heart valves

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14
Q

Describe Abnormal Periorbital ECM/ Exophthalmos

A

Autoimmune action on fibroblasts in ECM of eye
Most common in younger women
deposition of GAGS and influx of water into the orbital content

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15
Q

Throid disease

A

results in Goitre
most common in younger women
autoimmune over action of throid
deposition of the GAGS resulting in influc of water to the contents

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16
Q

Describe Collagen fibres

A

Thick parallel bundles
provide strength flexiblity and shear force
common in bone, tendon ligament

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17
Q

What are the Fibres within the CT

A

Elastic
Reticular and
Cartilage

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18
Q

Describe Reticular fibres

A

thin bundles with coating of glycoprotein
forms BM
made by fibroblasts
strength and support

19
Q

Describe Elastic fibres

A

Thinner than collagen
have coating of fibrillin that increases strength and flexibility
found in skin, BV and lungs

20
Q

Describe MArfan syndrome

A

chromesome 15
affects fibrillin therefore elastic fibres
Transforms growth beta cells= increased growth
1 in 20,000.

21
Q

What are two common cells found in the CT

A

Fibroblasts

Adipocyte

22
Q

Describe Fibroblasts

A

migratory widely spread

secretes components of the ECM eg. elastic fibres

23
Q

Adipose tissue

A

stores fat

found in skin/ around organs

24
Q

What are the classifications for CT

A

Embryonic of Mature

25
Q

What are the types of Mature CT

A

Connective tissue proper
Fluid CT
Supporting CT

26
Q

Describe Embryonic CT

A

Mesenchyme: reticular fibres formed
Mucous: umbilical cord

27
Q

CT proper: loose: areloar tissue

A

2 tissue types
widely distributed
strength, elasticity and support

28
Q

CT proper: Loose: Adipose

A

insulation, energy, temp

29
Q

CT proper loose described

A

many cells fewer fibers

30
Q

CT proper dense

A

more fibres fewer cells

31
Q

CT proper: Dense: Regular subtype

A

tendon. ligaments, aponeuroses

slow healing attachment

32
Q

Supporting CT: Cartilage: Hyaline

A

Dense network of collagen and elastic fibers

FLEXIBILITY AND MOVEMENT

33
Q

: Spongy bone

A

Porous, lacks osteons, produces RBC

34
Q

Combact bone

A

has osteons or haverians system

protection and support

35
Q

CELLS: Bone cell formation

A

1.(messencymal stem cells) Osteogenic cell- Ostoblasts- Osteocyte (mature bone)

36
Q

What do osteoclast do?

A

Bread down bone- monocyte

37
Q

Structure of Compact bone : Osteons

A
  1. lammellae
  2. Lacunae
  3. canaliculi
  4. central canal
38
Q

Bone healing process

A

Osteoclasts: reabsorb dead bone
CHondrocyet: lay down hyaline cartilage callus
osteoblast: lay new bone down
osteoclasts: remodel new bone

39
Q

Eythrocytes job

A

transport co2 and o2

40
Q

Neutrophils & monocytes

A

engulf bacteria (phagocytic)

41
Q

Basophils and mast cells

A

when immature they circulate
mature fixed in tissue
intensify inflammation

42
Q

Eosinophils

A

fight against parasitic worm & allergic response

43
Q

Lymphocytes:

A

Immune response

44
Q

Platelets

A

clotting

BIOSCI (29 decks)

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