Connective Tissue Flashcards by Joan Waipouri

Functions of CT

strengthens, binds, supports
transports- blood
Stored energy reserve- adipose/ fat

How well did you know this?

Not at all

Perfectly

Describe where CT is and its characteristics

Not found on body surface (blood cartilage)
Highly vascular (except for cartilage/ tendons)

How well did you know this?

Not at all

Perfectly

What is the equation for CT

CT= ECM + Cells

How well did you know this?

Not at all

Perfectly

Equation for ECM

ECM= GS + Fibers

How well did you know this?

Not at all

Perfectly

Where are protein fibers made and what dictates the structure of the CT

Protein fibers are secreted by the ECM

structure of the ECM largely dictates the structure

How well did you know this?

Not at all

Perfectly

Equation for GS

GS= h20+ proteins+ proteoglycans (sugars)

How well did you know this?

Not at all

Perfectly

What form Proteoglycans

GAGs + core proteins= proteoglycans

How well did you know this?

Not at all

Perfectly

GAG examples

Dermatan/Keratan/Chondroitin SULPHATE

or Hyaluronic acid

How well did you know this?

Not at all

Perfectly

What do GAGS do

Trap water

How well did you know this?

Not at all

Perfectly

Describe Hyaluronic Acid

Not sulphate/ covalently bonded
Binds cells together, Lubricates Joints and maintains shape of eyeballs
- Makes GS more liquid like
Produced by WBS, sperm and bacteria

How well did you know this?

Not at all

Perfectly

Chrondrotin Sulphate location

cartilage, bone, skin/ Blood vessel

How well did you know this?

Not at all

Perfectly

Keratan sulphate

bone/ cartilage/ cornea of eye

How well did you know this?

Not at all

Perfectly

Dermatan sulphate

skin, tendons Blood vessels and heart valves

How well did you know this?

Not at all

Perfectly

Describe Abnormal Periorbital ECM/ Exophthalmos

Autoimmune action on fibroblasts in ECM of eye
Most common in younger women
deposition of GAGS and influx of water into the orbital content

How well did you know this?

Not at all

Perfectly

Throid disease

results in Goitre
most common in younger women
autoimmune over action of throid
deposition of the GAGS resulting in influc of water to the contents

How well did you know this?

Not at all

Perfectly

Describe Collagen fibres

Thick parallel bundles
provide strength flexiblity and shear force
common in bone, tendon ligament

How well did you know this?

Not at all

Perfectly

What are the Fibres within the CT

Elastic
Reticular and
Cartilage

How well did you know this?

Not at all

Perfectly

Describe Reticular fibres

thin bundles with coating of glycoprotein
forms BM
made by fibroblasts
strength and support

Describe Elastic fibres

Thinner than collagen
have coating of fibrillin that increases strength and flexibility
found in skin, BV and lungs

Describe MArfan syndrome

chromesome 15
affects fibrillin therefore elastic fibres
Transforms growth beta cells= increased growth
1 in 20,000.

What are two common cells found in the CT

Fibroblasts

Adipocyte

Describe Fibroblasts

migratory widely spread

secretes components of the ECM eg. elastic fibres

Adipose tissue

stores fat

found in skin/ around organs

What are the classifications for CT

Embryonic of Mature

What are the types of Mature CT

Connective tissue proper Fluid CT Supporting CT

Describe Embryonic CT

Mesenchyme: reticular fibres formed Mucous: umbilical cord

CT proper: loose: areloar tissue

2 tissue types widely distributed strength, elasticity and support

CT proper: Loose: Adipose

insulation, energy, temp

CT proper loose described

many cells fewer fibers

CT proper dense

more fibres fewer cells

CT proper: Dense: Regular subtype

tendon. ligaments, aponeuroses | slow healing attachment

Supporting CT: Cartilage: Hyaline

Dense network of collagen and elastic fibers | FLEXIBILITY AND MOVEMENT

: Spongy bone

Porous, lacks osteons, produces RBC

Combact bone

has osteons or haverians system | protection and support

CELLS: Bone cell formation

1.(messencymal stem cells) Osteogenic cell- Ostoblasts- Osteocyte (mature bone)

What do osteoclast do?

Bread down bone- monocyte

Structure of Compact bone : Osteons

1. lammellae 2. Lacunae 3. canaliculi 4. central canal

Bone healing process

Osteoclasts: reabsorb dead bone CHondrocyet: lay down hyaline cartilage callus osteoblast: lay new bone down osteoclasts: remodel new bone

Eythrocytes job

transport co2 and o2

Neutrophils & monocytes

engulf bacteria (phagocytic)

Basophils and mast cells

when immature they circulate mature fixed in tissue intensify inflammation

Eosinophils

fight against parasitic worm & allergic response

Lymphocytes:

Immune response

Platelets

clotting