Connective Tissues Flashcards
Where are connective tissue cells mainly derived from
They are mainly derived from undifferentiated mesenchymal cells
What a connective tissues composed of
Cells such as fibroblasts, fibrocytes and adipose cells
Visible fibres such as collagen, elastic and reticulin
Ground substances such as proteoglycans, glycosaminoglycans, laminin and fibronectin
What are the different types of connective tissues with examples
Fibrous - loose and dense
Hard - cartilage and bone
Fatty - white and brown
Where do you find type I collagen
Skin
Where do you find type II collagen
Cartilage
Where do you find type III collagen
Liver, bone marrow and spleen
Where do you find type IV collagen
Basement membrane
Where do you find type V collagen
Placenta
What colour do extracellular fibres stain with H&E stain
Pink
What does loose connective tissue comprise of
Widely spaced thin collagen fibres
Fibroblasts/cytes
Unsteadiness ground substance
What does dense connective tissue comprise of
Closely spaced thick collagen fibres
Fibroblasts/cytes
Unstaffed ground surface
Can be regular or irregular
What type of collagen is reticulin
Type III collagen
What is the function of reticulin
Forms a supporting scaffold in many organs like bone marrow, liver, kidney, lymph node, spleen
What stain do you need to use to identify reticulin
Silver stain
What is a characteristic of white adipose tissue
Large cells with single fat globule in each cell
What is a characteristic of brown adipose tissue
Cells with many fat globules of fat in them
What is cartilage made up from
Cells such as chondroblasts and chrondrocytes
Extracellular matrix such as glycosaminglycans and proteoglycans
Extracellular fibres such as collagen and elastin
Is cartilage vascular or avascular
Cartilage is avascular
Where is hyaline cartilage found
Synovial joints
What are characteristics of hyaline cartilage
Chondrocytes in the lacunae surrounded by glassy amorphous matrix
No visible fibres
Perichondrium- fibroblasts and collagen
Where can elastic cartilage be found
Pinna
Epiglottis
What are characteristics of elastic cartilage
Visible elastic fibres in the matrix
Perichondrium- fibroblasts and collagen
Where can fibrocartilage be found
Annulus fibrous
Pubic symphysis
What are characteristics of fibrocartilage
Visible collagen fibres in the matrix
Perichondrium- finbroblasts and collagen
