Histology Of Bone Flashcards
What are the cells that make up bone
Osteoprogenitor cells
Osteoblasts
Osteocytes
Osteoclasts
What makes up the extracellular matrix in bone
Collagen
Calcium hydroxyapatite
Where are osteoblasts and osteocytes derived from
They are derived from embryonic mesenchyme or osteoprogenitor cells
What do osteoblasts and osteocytes secrete
Osteoid
What is osteoid
Unmineralised bone
How do osteoblasts and osteocytes connect to there surroundings
Via canaliculi
What are osteoclasts derived from
Monocytes
What do osteoclasts do
Absorb bone
What are the different types of bone by origin
Primary or woven
Secondary or lamellar
What are the different types of bone by mode of formation
Membranous
Endochondrial
What are the different types of bone by gross appearance
Spongy/cancellous
Compact
Osteons
Appositional
What does secondary bone form as
Osteons
What does the central Haversian canal contain
Blood vessel
What surrounds the Haversian canal
Concentric rings of lamellar bone with osteocytes
How is secondary bone examined
As a decalcified section with H&E stain
What are the arrows pointing to
Osteoblasts and osteocytes
What are the arrows pointing to
Osteoclasts
What are the arrows point to
Arrow one = Osteoblasts
Arrow two = Osteocytes
Third agree = Osteeord
Four arrow = Bone
What type of bone is this
Secondary bone
Identify the ossification going on in this tissue
At the far left is the resting cartilage and then the zone of hyperplasia
