↓ peristalsis
Constipation
5 classes of drugs for constipation
Psyllium
Polycarbophil
Fibers
Bulk Forming laxatives
Osmotic laxatives
Mineral oil
Lubricant laxatives
Anthraquinone glycosides
Castor oil
Bisacodyl***
Stimulant laxatives (↑ bowel tone)
Docusate
Emollient laxative
Safest and most functional
Bulk Forming laxatives
Mineral oil + Docusate
↑ systemic absorption of mineral oil
A/E: cathartic colon and melanosis coli
Stimulant laxatives
Act as surfactants
Emollient laxatives
Secretory laxatives
Stimulant laxatives