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From Flashcardlet > Cornea: Viral Infections > Flashcards

Cornea: Viral Infections Flashcards

0
Q

HSV-1

A

the prevalence of this herpesvirus is decreasing (probably related to hygiene practices) and age of inoculation increasing (making primary disease more symptomatic)

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1
Q

0.15%

A

approximate prevalence of external HSV ocular disease (at least one episode)

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2
Q

HSV-2

A

the prevalence of this herpesvirus has increased over the past few decades

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3
Q

congenital

A

only variant of herpes infection of the eye for which HSV-2 is prevalent

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4
Q

blepharoconjunctivitis

A

typical presentation of primary herpes infection of the eye (NOT reactivation)

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5
Q

ulcers, pseudomembranes

A

though both herpes and adenovirus can produce SPK early in their course the former demonstrates these (answer 1) in the conjunctiva whereas the latter shows these (answer 2)

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6
Q

3%

A

percentage of HSV infections that presented bilaterally in HEDS

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7
Q

immune dysfunction

A

suspicion for this should be high in bilateral HSV disease

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8
Q

topical or po antivirals

A

antivirals (topical or po), steroids, or both: primary ocular hsv

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9
Q

increased incidence

A

HSV in HIV: increased incidence, increased severity, both or neither

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10
Q

false

A

TRUE or FALSE: blepharoconjunctivitis is NOT typical of recurrent herpes infection

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11
Q

SPK, stellate ulcer, dendritic ulcer

A

typical sequence of findings in herpes simplex keratitis

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12
Q

ghost dendrite

A

often left behind when herpes epithelial keratitis results in significant stromal inflammation

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13
Q

topical or po antivirals

A

antivirals (topical or po), steroids, or both: herpes epithelial keratitis

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14
Q

prevention of neuropathy

A

Only long-term benefit that may result from antiviral treatment of herpes epithelial keratitis

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15
Q

HUS, TTP

A

two adverse effects of using valacyclovir in HSK in patients who are immunosuppressed

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16
Q

false

A

TRUE or FALSE: The absence of conjunctival injection or anterior chamber reaction makes active herpetic stromal keratitis unlikely

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17
Q

herpetic disciform keratitis

A

herpetic non-necrotizing keratitis vs herpetic disciform keratitis: epithelial edema is common

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18
Q

iridocyclitis with endothelial decompensation

A

Identify the type of herpetic infection: 3+ cell, 2+ flare, 1+ KPs, mild stromal edema

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19
Q

eccentric

A

location of epithelial defect relative to stromal inflammation in necrotizing herpes stromal keratitis (in one word)

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20
Q

steroids

A

PO antivirals are indicated in patients with epithelial keratitis on this medication

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21
Q

false

A

TRUE or FALSE: Topical antivirals help slow the duration of nonnecrotizing herpetic stromal keratitis

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22
Q

Q2H

A

usual starting interval for PF1% in herpetic stromal keratitis

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23
Q

necrotizing herpetic stromal keratitis

A

topical antivirals are discouraged in this form of herpetic infection

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24
Q

topical or po antivirals, steroids

A

antivirals (topical or po), steroids, or both: non-necrotizing herpetic stromal keratitis

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25
Q

po antivirals, steroids

A

antivirals (topical or po), steroids, or both: necrotizing herpetic stromal keratitis

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26
Q

po antivirals, steroids

A

antivirals (topical or po), steroids, or both: herpetic disciform keratitis

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27
Q

po antivirals, steroids

A

antivirals (topical or po), steroids, or both: herpetic iridocyclitis

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28
Q

aggressive lubrication

A

main therapy for neurotrophic ulcers

29
Q

metaherpetic ulceration

A

term for persistent epithelial defect over nonnecrotizing herpetic stromal keratitis (either result of neurotrophic mechanisms or devitalized stroma)

30
Q

topical steroids

A

treatment for secondary lipid keratopathy in herpetic stromal keratitis

31
Q

6 months

A

inflammation should be controlled for at least this time frame before considering PK in a patient with scarring from herpes

32
Q

tectonic PK

A

term for emergency PK in an eye with perforation or impending perforation

33
Q

20%

A

Incidence of shingles among people who have had chicken pox

34
Q

70%

A

incidence of ocular involvement in HZO

35
Q

VZV

A

HSV, VZV, or both: lid margin destruction, episcleritis, and scleritis

36
Q

true

A

TRUE or FALSE: unilateral ARN has been reported in conjunction with HZO

37
Q

33%

A

incidence of cranial nerve palsies in HZO

38
Q

both

A

VZV in HIV: increased incidence, severity, both or neither

39
Q

HIV-AIDS

A

These patients often suffer from persistent epithelial keratitis due to VZV

40
Q

50%

A

incidence of corneal hypoesthesia in VZV

41
Q

nummular keratitis, epithelial keratitis

A

two forms of VZV ocular disease that are clinically distinguishable from HSV

42
Q

true

A

TRUE or FALSE: orbital involvement of VZV may result in an orbital cellulitis picture

43
Q

60

A

The VZV vaccine is recommended for immunocompetent adults over this age

44
Q

72 hours

A

oral antivirals should be started within this time frame to prevent postherpetic neuralgia

45
Q

EBV

A

most common cause of acute dacryoadenitis

46
Q

EKC

A

type 1 EBV keratitis resembles this

47
Q

nummular keratitis

A

type 2 EBV keratitis resembles this

48
Q

syphilis

A

type 3 EBV keratitis resembles this

49
Q

interstitial keratitis

A

main type of ocular infection caused by EBV

50
Q

mononucleosis

A

patients with EBV keratitis should have a recent history of this

51
Q

po antivirals and steroids

A

antivirals (topical or po), steroids, or both: VZV keratitis

52
Q

pharyngoconjunctival fever

A

likely syndrome: flulike symptoms, sore throat, conjunctivitis

53
Q

adenoviral follicular conjunctivitis

A

term for typically appearing viral conjunctivitis caused by adenovirus

54
Q

URI

A

often precedes ocular involvement in EKC

55
Q

7-14 days

A

subepithelial infiltrates appear in EKC after this period

56
Q

pseudomembranes

A

feature that may distinguish EKC from acute hemorrhagic conjunctivitis

57
Q

adenovirus

A

this cause of viral conjunctivitis is commonly cicatrizing

58
Q

EKC

A

type of conjunctivitis associated with large central erosions

59
Q

pseudomembranes, subepithelial infiltrates

A

two indications for topical steroids in EKC

60
Q

2 weeks

A

typical infectious interval in EKC

61
Q

redness, tearing

A

patients with EKC with these symptoms should be considered infectious

62
Q

lid margin inspection

A

should be performed in any chronic follicular conjunctivitis

63
Q

trifluridine

A

treatment indicated in vaccinia keratoconjunctivitis

64
Q

episome

A

form taken on by nucleic acid of non-malignancy causing HPV strains

65
Q

influenza

A

common RNA virus that can induce inflammation and dysfunction in virtually any ocular tissue

66
Q

URI

A

conjunctivitis caused by RNA viruses usually presents along with this

67
Q

mumps

A

Name the causative agent: scleritis within two weeks following bilateral pain at the angle of the jaw

68
Q

polio-like syndrome

A

acute hemorrhagic conjunctivitis may be followed by this in 1 in 70,000 cases

69
Q

CD4 cell

A

primary cell that mediates corneal inflammation in herpes epithelial keratitis

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