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Flashcards in CSF and ICP Deck (21):
1

CSF - location

Travels around the brain and spinal cord

2

CSF - production

Produced in the choroid plexus
- by the secretory epithelium

3

Location of the choroid plexus

Found in the lateral, 3rd and 4th ventricles

4

CSF - reabsorption

Absorbed continuously into the venous circulation by arachnoid granulations and into the dural venous sinuses

5

CSF - function

Mechanical protection
- allows the brain to be suspended in the cranial cavity
Transports hormones
Allows the exchange of nutrients
Allows the exchange of waste products

6

Name the different ventricles of the brain

Lateral (right and left)
3rd ventricle
4th ventricle

7

Meninges - functions

Protective coverings of the brain and spinal cord

8

Meninges - layers (3)

Dura mater
Arachnoid mater
- has granulations, where CSF drains
Pia mater

9

Sub-arachnoid space - location

Between the arachnoid and pia mater

10

Where is the location of CSF?

Sub-arachnoid space

11

CSF pathway

Produced in choroid plexus
Travels from lateral ventricles and through the inter ventricular foramina (foramen of monroe) and into the 3rd ventricle.
CSF then travels through the cerebral aqueduct of selves and into 4th ventricle

12

Where does CSF go after it reaches the 4th ventricle

There are different directions for CSF to travel to the sub-arachnoid space:
- paired lateral aperture (via foramen of lushka)
- single medial aperture (via foramen of magnesia)

13

CSF accumulation

abnormal balance between the amount of CSF produced the amount drained

14

Conditions related to CSF accumulation

Hydrocephalus

15

Investigation when there is excess CSF in the body

Lumbar puncture

16

Where is lumbar puncture carried out?

Below L2 vertebral level (so as not to damage spinal cord)

17

Raised ICP

Increase in pressure within the cranial cavity

18

What happens in the cranial cavity when there is a raised ICP

Raised ICP means that something needs to get compressed and pushed out of the cranial cavity in order to maintain a constant intracranial volume

19

Causes of raised ICP

Over production of CSF
Inadequate drainage of CSF
Brain tumour
Stroke
Meningitis
Hydrocephalus

20

Blood brain barrier - function

Protects brain and ensures that the movement from circulatory to nervous system is highly restricted.

21

Disadvantages of the blood brain barrier

Obstacle for drug delivery to the CNS