cv - lymphatic system Flashcards

1
Q

what makes up the lymphatic system

A

Network of organs, vessels and tissues

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2
Q

describe the accessory fluid

A

return route to the blood

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3
Q

the lymphatic system is vital to what other system in the body

A

immune system

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4
Q

it is complementary to what other body system

A

Cardiovascular system

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5
Q

what is lymph

A

Fluid of the system (clear, pale yellow) ~interstitial fluid; 32L/day drained into system; returns lost plasma proteins to bloodstream in lymphatic vessels

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6
Q

what is lymphatic tissue

A

Structures and organs containing lymphatic tissue – a specialised connective tissue that contains large numbers of lymphocytes

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7
Q

what is bone marrow

A

Stem cells develop into RBC & WBC

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8
Q

whats the 3 functions of lymphatic system

A

Drain tissue spaces of excess interstitial fluid and return it to the cardiovascular system.

Transport dietary lipids and lipid-soluble vitamins (A, D, E & K) from the GI tract to the blood

Protect the body from foreign cells, microbes and cancer cells through immune responses.

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9
Q

what are the smallest lymphatic vessel

A

lymphatic capillaries

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10
Q

explain lymphatic capillaries

A

Slightly larger than blood capillaries, closed-ended

Pressure in tissues will force fluid into them

Overlapping endothelial cells, like a one-way valve, so fluid not flow out

Found throughout body except in CNS, bone marrow, portions of spleen and avascular tissues.

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11
Q

lymphatic capillaries merge to form what

A

form larger vessels: lymphatic ducts

  • Thin walled and more valves than veins
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12
Q

lymphatic vessels periodically have what

A

lymph nodes

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13
Q

explain lymph nodes

A

Lymphocytes in capsular structure

The left thoracic duct—-> Left subclavian vein at junction with jugular

Right lymphatic duct —> Right subclavian vein

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14
Q

explain lymph flow

A

Unlike cardiovascular, system has no pump

Muscle contraction

1-way valves,

Respiratory pressure

Smooth muscle contraction in lymph vessel wall.

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15
Q

lymphatic organs can be divided into what

A

primary and secondary organs

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16
Q

what are the primary lymphatic organs

A

Thymus

Red bone marrow
- Provide appropriate environment where stem cells divide & mature into B & T cells

17
Q

what are the secondary lymphatic organs

A

Lymph nodes
Spleen
Lymphatic nodules

18
Q

secondary lymphatic organs are the sites where most what occurs

A

most immune responses occur

19
Q

explain the thymus structure

A

Two lobed organ
Between lungs, above heart

20
Q

what are the cells in the thymus

A

immature T cells
mature T cells

21
Q

explain immature T cells in thymus

A

migrate from bone marrow to cortex of thymus where multiply and mature

22
Q

explain mature T cells of thymus

A

then enter blood and populate lymph nodes, spleen and other lymphatic tissues.

23
Q

what are lymph nodes structure and how many and where located

A

~600 bean-shaped organs along lymph vessels

Scattered throughout the body
- Concentrated near mammary glands, axillae (armpits) & groin

24
Q

explain cells in lymph nodes

A

Contain plasma cells, mature B-cells, T-cells, dendritic cells and macrophages

25
what do lymph nodes do
Filter lymph, trap foreign substances Macrophages & lymphocytes destroy most foreign substances
26
explain germinal centres in lymph nodes
Aggregations of B lymphocytes Rapidly proliferating and differentiating upon stimulation with antigen.
27
explain the spleens shape and location
Oval, largest single mass of lymphoid tissue On LHS between stomach & diaphragm
28
name the 2 tissue types of the spleen
Two types of parenchymal tissue: white pulp red pulp
29
explain the white pulp parenchymal tissue of the spleen
lymphatic – lymphocytes & macrophages surrounding central arteries
30
explain the red pulp parenchymal tissue of the spleen
blood-filled venous sinuses and splenic cords with RBC, macrophages, lymphocytes, plasma cells & granular leukocytes - Destroys worn or defective blood cells & platelets - Stores platelets - Production of blood cells in foetal life Remove if ruptured as severe i.p. (intraperioneal) haemorrhage & shock; red bone marrow & liver can take over functions.
31
describe lymphatic nodules
Egg-shaped masses of lymphatic tissues NOT surrounded by capsule
32
Mucosa-associated lymphatic tissue (MALT) found is in what
GI tract Urinary tissue Reproductive tissue Respiratory tissue Some in large aggregates e.g., tonsils, Peyer’s patches (in ileum).
33
how much of the fluid exchange across walls of capillaries goes to lymphatics
1/10 volume
34
describe Fluid exchange across walls of capillaries
hydrostatic pressure out osmotic pressure into capillaries