female reproductive system Flashcards

(47 cards)

1
Q

what is The only human organ system significantly different between female and males

A

human reproductive system

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2
Q

what in both sexes is designed to facilitate the continuation of the species

A

anatomy and physiology

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3
Q

wheres the uterus located

A

between bladder & rectum.

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4
Q

what are the 2 female gonads and their function

A

Female gonads
Two ovaries; produce egg cells (ova) & sex hormones

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5
Q

whats the shape of the ovaries

A

almond-shaped organs (3x1.5x1cm)

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6
Q

what is within the capsule of the ovaries

A

tunica albuginea

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7
Q

what happens in the outer cortex of the ovaries

A

germ cells develop

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8
Q

what is found in the inner medulla of the ovaries

A

major arteries & veins

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9
Q

what is oogenesis

A

production of secondary oocyte

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10
Q

what is ovulation

A

release of secondary oocyte

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11
Q

what the name of the fertilised oocyte

A

zygote

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12
Q

what happens after ovulation

A

After ovulation, follicle still has important function:
- transformed into glandular structure ‘corpus luteum’: secretes progesterone (& oestrogen), lasts through pregnancy, otherwise 10-12 days then degenerates (corpus albicans)

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13
Q

where does your life as an egg actually start

A

Your life as an egg actually started in your mother’s developing ovary, before she was born; you were wrapped in your mother’s foetal body as it developed within your grandmother.

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14
Q

explain the process of oogenesis when oogonium develops into a zygote

A

during foetal development meiosis 1 begins

then

after puberty, primary oocytes complete meiosis 1, which produces a secondary oocyte and a first polar body that may or may not divide again

then

secondary oocyte begins meiosis 2

then

a secondary oocyte (and first polar body) is ovulated

then

after fertilisation, meiosis 2 resumes. the oocyte splits into a ovum and a second polar body

then finally

the nuclei of the sperm cell and the ovum unite, forming a diploid (2n) xygote

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15
Q

what is oogenesis for and when does it occur

A

Development of oogonium to mature ovum

Occurs at different stages of female life

eg:
- pre natal -> mitosis and growth, forming primary oocyte from oogonium.
- puberty -> meiosis 1, forming secondary oocyte
- fertilization -> meiosis 2 , forming ovum

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16
Q

name the 9 stages of the ovarian cycle

A

1 = primordial follicle;
2 = primary follicle;
3 & 4 = growing primary follicle;
5 = secondary follicle with antrum forming;
6 = mature follicle;
7 = ruptured follicle, ovulation; 8 = corpus luteum;
9 = corpus albicans.

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17
Q

name the secondary follicles

A

Oocyte

Zona pellucida = layer of glycoprotein

Granulosa cells

Thecal cells = = cells adjacent to granulosa cells but in the ovarian stroma, form a layer around the follicle;

Primordial follicles

An atretic (degenerating) follicle (single arrow)

both the zona pellucida and thecal cell types work together to produce oestrogens.

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18
Q

how many oviducts are there and whats another name for them

A

2
fallopian tubes

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19
Q

whats the length of the uterine tubes and where do they branch from and to

A

10cm long from ovary to uterus

20
Q

explain the shape of the uterine tubes

A

Trumpet-shaped infundibulum at ovary with feathery projections (fimbrae)

21
Q

explain some of the arts to the uterine tubes

A

Ampulla = middle part of tube

Narrow isthmus near uterus

SMC ( smooth muscle cell) wall

convoluted mucosa

Ciliated & secretory cells

22
Q

what do Ciliated cells of oviduct do

A

Sweep the egg along the oviduct towards the uterus

23
Q

describe the uterus shape

A

Pear-shaped
size (7 x 4 x 2.5 cm)

24
Q

what does the uterus do

A

Harbours embryo, provides nutrition, expels foetus at end of development

25
whats the the main parts of the uterus
Fundus (top), body, cervix Cervical canal to vagina Cervical glands secrete mucus
26
how many layers does the uterus have and name them
3 endometrium myometrium perimetrium
27
what ages are at rick of cervical cancer
20-60 years
28
what causes an increased risk of obtaining cervical cancer
smoker, early sexual activity, STIs & cervical inflammation begins lower cervix epithelial cells
29
how fast does cervical cancer develop
Develops slowly - local lesion –> years
30
does cervical cancer spread
Invasive - spread to subepithelial connective tissue leading to hysterectomy
31
how can cervical cancer be detected early
Detect early by cervical smear - moving from solely cytology to additional HPV testing
32
what happens in a cervical smear
scrapes loose cells (epithelial cells) form the cervix to be microscopically examined via a 5-point scale: - Class 1 = no abnormal cells - Class 5 = invasive cancer
33
what do cervical cancer cells look like compared to normal cells when analysed in a smear test
large darker staining nuclei with irregular shapes normal cells have small , regular nuclei
34
explain the vagina
10cm long tube from uterus to outside Receives penis during intercourse Allows menstrual flow & childbirth Wall has outer smooth muscular layer Inner mucous membrane produces lubricating secretions Hymen at vaginal opening (thin mucous membrane)
35
the female reproductive system is under the control of what
of hormonal & nervous regulation (as in males)
36
the Development of reproductive organs & normal function depends on what
on relative levels of a number of hormones
37
what happens in females during puberty
1st menstrual bleeding = menarche Enlargement of: - Vagina - Uterus - Uterine tubes - External genitalia Breasts deposit fat, develop ducts Pubic & axillary hair grows Voice changes Development of sexual drive
38
what causes puberty to occur
increased oestrogen & progesterone by ovaries Due to increased FSH & LH (cyclic secretion) Due to GnRH (Gonadotropin-Releasing Hormone) from the hypothalamus
39
how long does the menstrual cycle last
Typically 28 days long
40
explain the day 1 of the menstrual cycle
= menses = mild haemorrhage when uterine epithelium sloughed off & expelled (lasts 4-5 days) - Follicular/Proliferative Phase (follicles rapidly develop/uterine mucosa rapid proliferate)
41
explain day 14 of the menstrual cycle
= ovulation (timing varies between & within individual) - Luteal/Secretory Phase (corpus luteum/maturation, secretion uterine glands)
42
what controls the menstrual cycle events
Hormones: Oestrogen Progesterone FSH LH
43
explain the hierarchy of control
ovaries --> pituitary uterus --> hypothalamus feedback control
44
explain the process of the ovarian cycle
FSH from anterior pituitary - initiates development of 1o follicles 25 folicles mature - But only one develops, the rest degenerate As folicles enlarge - begin to secrete oestrogen High levels - cause +ve feedback to anterior pituitary so rapid FSH & LH secretion= LH surge - initiates ovulation Once egg released - granulosa cells of empty follicle become luteal cells & secrete progesterone High progesterone – negative feedback on GnRH from hypothalamus, so decreases FSH & LH from anterior pituitary Rapid fall in oestrogen & progesterone - as corpus luteum atrophies, results in menses
45
explain the process of the uterine cycle
Oestrogen causes epithelial cells of basal layer to rapidly divide to replace cells of functional layer which were sloughed Stimulates synthesis of progesterone receptors on uterine cells Low cuboidal & columnar endometrial cells form folds - spiral glands with spiral arteries After ovulation - progesterone from corpus luteum results in cellular hypertrophy As corpus luteum degenerates - low oestrogen & progesterone causes lining to degenerate Spiral arteries constrict Ischaemic then necrotic - menses Myometrial SMC contraction to expel menstrual fluid The cycle begins again
46
what happens if the egg is fertilised
Developing embryonic mass secretes human chorionic gonadotropin (HCG) HCG prevents degeneration of corpus luteum Thus oestrogen & progesterone levels do not fall & so menses not occur.
47
how does the pill prevent pregnancy
Birth control pill - oral contraceptives Synthetic oestrogen & progesterone Negative feedback on pituitary Prevents LH surge, so no ovulation