pulmonary ventilation Flashcards

(36 cards)

1
Q

air moves in and out lungs cos of what

A

pressure diff
high to low

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2
Q

explain boyles law

A

Gas law

States that the pressure
of a gas is inversely proportional to its volume

P1V1=P2V2

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3
Q

explain muscle respiration in terms of when breathing in

A

Inspiration
breathing in, inhalation

Diaphragm
constriction causes dome to flatten

Muscles that elevate ribs & sternum e.g.,
- External intercostals
- Pectoralis minor
- Scalenes (neck)

increase size of thoracic cavity

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4
Q

explain muscle respiration in terms of breathing out

A

Active Expiration
breathing out, expiration

Muscles that depress ribs & sternum e.g.,
- Internal intercostals
- Abdominal muscles
decrease size of thoracic cavity

Passive Expiration
elastic lung recoil:
- Elastic fibres in alveolar wall
- Surface tension of fluid film lining alveoli

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5
Q

name the muscles of inhalation

A

sternocleidomastoid

scalenes

external intercostals

diaphragm

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6
Q

name the muscles of exhalation

A

internal intercostals

external oblique

internal oblique

transversus abdominis

rectus abdominis

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7
Q

explain the changes of thoracic cavity during inhalation and exhalation

A

on inhalation the sternum moves outwards

on inhalation the diaphragm contacts and moves downwards

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8
Q

air movement results from diff between what

A

atmospheric pressure (760mmHg)
and
Alveolar pressure
Palv (inside alveolus)
- Decrease = air moves into lungs

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9
Q

summarise the cycle of air movement

A

at rest (diaphragm relaxed):
- alveolar pressure = 760mm Hg

during inhalation (diaphragm contracting):
- alveolar pressure = 758mm Hg less than the atmospheric = so air moves in

during exhalation (diaphragm relaxing):
- alveolar pressure = 762 mm Hg, more than atmosphereic = so air moves out

atmospheric pressure is remained at 760mm Hg throughout cycle

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10
Q

what is pleural cavity

A

space between lung & chest wall

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11
Q

what is found inside pleural cavity

A

Pip (written as = big P, tiny ip)

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12
Q

what happens if If Pip < Palv

A

alveoli expand (= normal)

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13
Q

what is Pneumothorax

A

If air enters pleural cavity, Pip= atmospheric pressure

alveoli cannot expand

lungs collapse

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14
Q

what can be seen in an Pneumothorax CT scan

A

Lung collapsed

Dark, air-filled space

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15
Q

name 3 other factors that affect rate of pulmonary airflow

A

Surface tension of alveolar fluid

Lung compliance

Airway resistance

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16
Q

explain the 3 factors that can affect rate of pulmonary airflow

A

Surface tension of alveolar fluid:
- Overcome by surfactant
lipoprotein molecules in alveolar fluid prevent alveoli collapsing & allowing lungs to expand
- Less surfactant in premature infants causes
‘respiratory distress syndrome’

Lung compliance
- Capacity for stretching

Airway resistance
- Controlled by pressures and airflow

17
Q

what causes interpleural pressure

A

pleural cavity

with can lead to pneumothorax

18
Q

what is the Role of Surfactant in Lung

A

Decreases surface tension of alveoli to prevent them from collapsing.

19
Q

describe the diff between immature vs mature lung

A

Immature lung:
Not conducive to gas exchange

Mature lung:
Larger surface area

20
Q

what does lung compliance mean

A

Effort required to stretch lungs & thoracic wall

21
Q

explain high compliance

A

high compliance = easy expansion

e.g., thin balloon has high compliance as easy to inflate

22
Q

how is there effort required to stretch the lungs and thoracic wall

A

Elastic forces of the lung:

presence of elastic & collagen fibres

surface tension.

23
Q

explain airway resistance

A

Resistance of the respiratory tract to airflow
- during inhalation and exhalation

Decreases as diameter of airways increases
- walls pulled outwards, smooth muscle relaxation

24
Q

explain air volume as we breathe

A

Only small proportion of air in lungs exchanged during single, quiet respiratory cycle
- inhale + exhale

Increase by inhaling more vigorously & exhaling more completely

Maximum effort of inspiration
- Volume of air in lungs = Total lung capacity

25
name the 4 pulmonary volumes
tidal volume Inspiratory reserve volume Expiratory reserve volume Residual volume
26
explain the pulmonary volumes tidal volume
amount of air moved into or out of lungs during a normal inspiration or exhalation (~500ml)
27
explain the pulmonary volume Inspiratory reserve volume
amount of air that can be inspired forcefully after inspiration of normal tidal volume (~3100ml)
28
explain the pulmonary volume Expiratory reserve volume
amount expired forcefully after normal expiration (~1200ml)
29
explain the pulmonary volume Residual volume
still remaining in respiratory passages & lungs after most forceful expiration (~1200ml)
30
what are pulmonary capacities
Sum of two or more pulmonary volumes
31
name the 4 pulmonary capacities
Inspiratory capacity functional residual capacity vital capacity total lung capacity
32
explain the pulmonary capacity: Inspiratory capacity
tidal vol + inspiratory reserve vol amount can inspire maximally after normal expiration (~3600 ml)
33
explain the pulmonary capacity: Functional residual capacity
expiratory reserve vol + residual vol amount remaining in lungs after normal expiration (~2400 ml)
34
explain the pulmonary capacity: Vital capacity
inspiratory reserve vol + tidal vol + expiratory reserve vol max can expel after max inspiration (~4800 ml)
35
explain the pulmonary capacity: Total lung capacity
inspiratory reserve vol + expiratory reserve vol + tidal vol + residual vol (~6000ml)
36
explain how we measure these volumes and capacities
Spirometry: process of measuring volumes of air that move in & out of respiratory system Spirometer: device used to measure these pulmonary volumes - Values obtained useful in diagnosing problems with pulmonary ventilation, e.g., asthma.