Cystoisosporosis of carnivores

Question 1

Cystoisospora species of dogs

Answer 1

C. canis
C. ohionensis
C. neorivolta
C. burrowsi

Question 2

Cystoisospora species of cats

Answer 2

C. felis
C. rivolta

Question 3

Cystoisospora of carnivores - PH

Answer 3

rodent

Question 4

Cystoisospora of carnivores - location

Answer 4

• SI
• C. ohionensis - also cecum and colon

Question 5

Cystoisospora of carnivores - transmission

Answer 5

oral ingestion

Question 6

Cystoisospora of carnivores - Life cycle

Answer 6

1) Exogenous sporogony: unsporulated oocyst is shed in feces of FH and sporulates in environment. Sporulated oocyst is ingested by final host.
2) Endogenous merogony: excyst in the intestines and releases sporozoites. Each sporozoite invades an epithelial cell.
Merogony: binary fission inside cell –> schizont/meront with merozoites. Cell ruptures and releases merozoites, which infects new cells.
3) Endogenous gametogony: inside intestinal cells, merozoites become microgamete (male) and macrogamete (female). Nuclei fuses –> zygote –> oocyst. Unsporulated oocyst is shed in feces.
4) Paratenic host (rarely): invades extraintestinal tissue and produce a single dormant cyst without causing disease. Hypnozoites inside.

PP: C. canis: 9 days, C. felis: 10-11 days, C. rivolta/cati: >14 days

Question 7

Cystoisospora of carnivores - Pathogenesis

Answer 7

• Villous atrophy, necrotic enteritis, enterocyte metaplasia, crypt hyperplasia, digestive function is impaired.
• Young most susceptible.

Question 8

Cystoisospora of carnivores - clinical signs

Answer 8

Watery, yellow diarrhoea, anorexia, weak infection is asymptomatic.

Question 9

Cystoisospora of carnivores - diagnosis

Answer 9

flotation

Question 10

Cystoisospora of carnivores - treatment

Answer 10

• toltrazuril, diclazuril
• ATB

Question 11

Cystoisospora of carnivores - PH