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Flashcards in deck 6 Deck (48)
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1

What syndromes could potentially cause a total body skin peeling with a sunburn-like rash in newborns?

Staphylococcal scalded skin syndrome, Staphylococcal TSS, and Streptococcal TSS

2

Which toxins are the major causes of Staph TSS?

TSST-1, enterotoxin B, enterotoxin C

3

Which toxins are the major causes of Staph Scalded skin syndrome?

exfoliative toxin A and B

4

General mechanisms of transmission (review)

aerosol, direct contact, sexual contact, vectors, fecal:Oral (water), food, endogenous, nosocomial

5

What is a flat, sunburn-like rash called?

macular erythroderma

6

What is a bumpy rash called?

papular

7

What is a flat, sunburn-like rash with bumps called?

maculo-papular

8

What is a rash with hives called?

urticarial

9

What is a rash with small fluid-filled sacs called?

vesicular

10

What is a rash with large fluid-filled sacs called?

bullous

11

What is a rash with fluid-filled sacs with yellow, white, or green pus called?

pustular

12

What is a rash with small rose-shaped spots called?

petechial

13

what usually causes the rose-shaped spots of the petechial rash?

blood vessel damage in gram-negative infections

14

What is a purple rash due to blood leaving the blood vessels called?

purpuric

15

What is a floor burn-like rash that eventually becomes a black scab called?

eschar

16

Which type of rash may be associated with menstrual TSS?

macular erythroderma

17

what type of rash is associated with chickenpox?

papular rash

18

what type of rash may be seen with staphylococcal impetigo?

pustular rash

19

What type of rash is associated with a cutaneous anthrax infection?

eschar

20

What is a primary pathogen?

A microbe that, when present in the host, typically causes illness

21

What is an opportunistic pathogen?

Often normal flora microbe that causes illness when the host is immune compromised.

22

What are the four types of primary pathogens?

exotoxemia, invasive extracellular, exotoxemia + invasive extracellular, invasive intracellular

23

Tetanus, Diphtheria, Cholera, TSS,Scarlet Fever fall into which category of primary pathogen?

exotoxemia

24

Haemophilus influenzae, Streptococcuspneumoniae, Neisseria meningitidis fall into which category of primary pathogen?

invasive extracellular

25

Staphylococcus aureus, Streptococcus pyogenes fall into which category of primary pathogen?

exotoxemia + invasive extracellular

26

Mycobacterium tuberculosis, Salmonella typhi, Listeria monocytogenes fall into which category of primary pathogen?

invasive intracellular

27

What are examples of the major categories exotoxins (review)?

ADP ribosylating enzymes, depurinating enzymes, cytolysins/cytotoxins, proteases, superantigens

28

T/F: Many exotoxins are referred to as A:B or B:B toxins, where A=active and B=host cell binding.

T

29

Where are many exotoxins encoded?

bacteriophages, plasmids, or pathogenicity islands

30

On what does immunity to exotoxin illnesses depend?

neutralizing antibodies