Devo Lect 2 - Test organisms

Question 2

Drosophila

Answer 2

Well established genetics, complete genome, long history, short life cycle, polytene chromosomes, mutant analysis

Question 3

Polytene Chromosome

Answer 3

Salivary glands of drosophila make DNA copies without mitosis - instead of one strand you get 1000 identical copies together; can see banding patterns and chromosomal puffs

Question 4

C. elegans

Answer 4

nematode, established genetics, complete genome, life cycle 3 days, hemaphrodite, complete fate map (made with laser or stains tests), mutant analysis

Question 5

Xenopus laevis

Answer 5

Vertebrate, external eggs, many large eggs, clear shell, gene expression system (can insert proteins etc)

Question 6

Gallus domesticus

Answer 6

Amniote, external development, can make windows in egg; chimera studies: add some cells from different species and trace their development

Question 7

Mus musculus

Answer 7

Mammal, short lifespan; genome sequenced, very similar to humans; lots of transgenics and knockouts

Question 8

Danio rerio (zebrafish)

Answer 8

embryological development 3 days; transparent embryos (easy to see and label); mutant analysis, molecular techniques (transgenenic, antisense, RNAi)