Differentiated thyroid cancer Flashcards
(54 cards)
what is the most common and second common type of thyroid cancer
papillary then follicular
what is the most common and second common type of thyroid cancer
papillary then follicular
what are DTC driven by?
TSH
what do thyroid cancers secrete?
thyroglobulin
Is DTC common in children?
no
what happens in the rate of women over the age of 40?
the rate plateaus
what is the epidemiology of men in DTC?
age increases, risk increases
what strong association is linked with DTC?
radiation exposure
What is the association with diet, FH, malignancies, smoking
NONE
what is the most common presentation of DTC?
small palatable nodes, some present with pathological fractures (uncommon)
how does papillary DTC spread?
via lymphatics
what disorder is associated with papillary thyroid canceR?
hashimotos thyroiditis
what is the mortality rate at 10 years-
What causes incidence of follicular carcinoma to be higher in certain regions?
iodine deficinecy
How does follicular carcinoma spread?
haematogenous/ lymphatics
What is the main investigation for papillary/ follicular carcinoma?
USS with fine needle aspiration of lesion
if vocal cord palsy is suspected what test should be done prior to surgery?
laryngoscopy
what is the main stay treatment for DTC?
surgery- sub total thyroidectomy
what does AMES stand for?
Age, Metastases, Extent of primary tumour, Size of primary tumour
what are some low risk patients?
young, 20year survival is 99%
who are in the AMES high risk category
metastases, extra thyroidal disease with papillary cancer, capsular invasion with follicular carcinoma
when should a sub/ tool thyroidectomy take place?
in high risk patients
what is a common side effect post op?
hypocalcaemia- low T2/3/4
Do you want the TSH to be high before or after surgery?
Before
