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Endocrine > Pharmacology > Flashcards

Flashcards in Pharmacology Deck (27):
1

are endocrine glands ductless or have ducts?

ductless

2

what are 3 ways of specifying different signalling?

chemically distinct hormones, specific receptors and distribution of receptors across target cells

3

What are the two main endocrines in the body

pituitary and hypothalamus

4

what are some functions of the endocrine system?

regulate h2o and electrolyte balance, nutrient metabolism. Promote growth and development, control reproduction, regulate RBC production

5

how do endocrine glands travel?

In blood to site of cells

6

Oxytocin and insulin are what type of hormone?

glycoprotein and peptide

7

what is cortisol and testosterone hormone?

steroids

8

what type of hormone is adrenaline?

tyrosine

9

Are amines hydrophilic or hydrophobic?

hydrophilic

10

amines are transported freely?

yes

11

Ca exocytosis stimulates amine synthesis?

yes

12

peptides and proteins are not Ca driven and are transported bound

FLSE FALSE FLASE

13

Is steroids hydrophobic or hydrophilic?

hydrophobic

14

how are steroids transported /

bound 90% of the time

15

Are steroids stored?

NO

16

What is needed to transport steroids nd thyroxine?

carrier proteins

17

cortisol binding globulin binds what?

cortisol

18

What is thyroxine bound by

thyroxine binding globulin

19

what does sex steroids binding globulin bind?

testosterone and estradiol

20

do proteins and peptides require transportation?

noooooo

21

can free or bound hormones transport across capillary wall?

free

22

How does hormone get eliminated form the body?

metabolism by the liver and excretion by the kidneys

23

what are receptor kinases activated by?

proteins and peptides

24

What are g protein coupled receptors activated by?

amines

25

what isdoesclass 1 nuclear receptors activated by?

steroids

26

what is the hybrid class activated by?

thyroid hormone

27

what is class 2 nuclear receptors activated by

lipids