Flashcards in Pharmacology Deck (27)
are endocrine glands ductless or have ducts?
what are 3 ways of specifying different signalling?
chemically distinct hormones, specific receptors and distribution of receptors across target cells
What are the two main endocrines in the body
pituitary and hypothalamus
what are some functions of the endocrine system?
regulate h2o and electrolyte balance, nutrient metabolism. Promote growth and development, control reproduction, regulate RBC production
how do endocrine glands travel?
In blood to site of cells
Oxytocin and insulin are what type of hormone?
glycoprotein and peptide
what is cortisol and testosterone hormone?
what type of hormone is adrenaline?
Are amines hydrophilic or hydrophobic?
amines are transported freely?
Ca exocytosis stimulates amine synthesis?
peptides and proteins are not Ca driven and are transported bound
FLSE FALSE FLASE
Is steroids hydrophobic or hydrophilic?
how are steroids transported /
bound 90% of the time
Are steroids stored?
What is needed to transport steroids nd thyroxine?
cortisol binding globulin binds what?
What is thyroxine bound by
thyroxine binding globulin
what does sex steroids binding globulin bind?
testosterone and estradiol
do proteins and peptides require transportation?
can free or bound hormones transport across capillary wall?
How does hormone get eliminated form the body?
metabolism by the liver and excretion by the kidneys
what are receptor kinases activated by?
proteins and peptides
What are g protein coupled receptors activated by?
what isdoesclass 1 nuclear receptors activated by?
what is the hybrid class activated by?