reproductive endocrinology Flashcards
(48 cards)
how long does it take oogenesis to occur compared to spermatogenesis
oogenesis- years, spermatogenesis- 72 days
when does oogenesis begin in women
utero, suspended for years and then beings again in puberty
when does oogenesis cease?
menopause
what is the first recognisable germinal cell called
primordial germ cell
where does the primordial germ cell migrate to by week 6 of embryo development
genital ridge
what is oogonia
the completion of last pre- biotic divisions to oocytes
what type of cell enters meiosis
oocytes
the development of polar bodies in first stage meiosis produces unequal divisions of oocytes, true or flase
true
how long does the ovarian cycle last
28 days
what is the first and second half of cycle called
follicular phase and luteal phase
What happens in the follicular phase
primary oocyte surrounded by granulose cells- primary follicle. Each oocyte can produce a single ovum. Oocytes then grow and follicles expand and become differentiated
what happens to the follicular cells after ovulation
transformed into the corpus luteum
what does the corpus lute secrete
progesterone
what does the gonadal releasing hormone act on and what does this structure then secrete
acts on anterior pituitary FSH- development of follicles, LH- follicle maturation, ovulation, corpus lute development
what cells produce androgen
theca
what converts the theca cells to oestradiol
granulose- thickens endomettrium
what do the theca cells convert androgen to?
oestrogen
what organ takes over the role of progesterone secretion after 6 weeks
placenta
where does glandular oestrogen synthesis occur?
granulosa and theca cells of the ovaries as well as the corpus luteum
what do LH tell granulose cells to produce
pregnenolone
what produces progesterone?
pregnenolone
what does oligomenorrhea mean
reduction in frequency of periods
what is primary amenorrhea
failure of puberty at age 16
what is secondary amenorrhea
cessation of periods for more than >6months
