DM Drugs Rapid Review Flashcards Preview

Pharmacology > DM Drugs Rapid Review > Flashcards

Flashcards in DM Drugs Rapid Review Deck (15):
1

rapid insulin includes`

lispro, aspart, glulisine

2

very long acting insulin includes

detemir, glargine, ultralente

3

glargine usually:

precipitates in subQ tissue

4

detemir binds:

albumin

5

-glitazone drugs

increase insulin sensitivity via PPARy

6

-glinide drugs

similar to sulfonylureas, but bind to different site on K+ channel (stimulate insulin release)

7

-gliptin

DPP4 inh --> increased GLP-1

8

-flozin

SGLT2 inb in PCT

9

acarbose

inh of a-glucosidase in intestine

10

miglitol

inh of a-glucosidase in intestine

11

pramlintide

amylin analogue which slows gastric emptying and ultimately decreases glucagon

12

exenatide

GLP-1 analogue

13

liraglutide

GLP-1 analogue

14

metformin

inhibits gluconeogenesis, increases glycolysis and insulin sensitivity, don't give in renal pts due to risk of lactic acidosis

15

chlorpropamide, tolbutamide, glimepiride, glipizide, glyburine

sulfonylureas