DNA and cell division Flashcards
(19 cards)
What does a nucleotide consist of ? (3)
1 Pentose sugar
1 Nitrogenous base
1 Phosphate group
What process and what bonds are formed between neucleotides?
Condensation reactions form phosphodiester bonds
What are the complementary base pairs
Adenine - Thymine
Cytosine - Guanine
How is Eukaryotic DNA similar to Prokaryotic DNA? (2) Spy fam dog
Identical nucleotide structure
Nucleotides are both joined via phosphodiester bonds
How is Eukaryotic and Prokaryotic DNA different?
3 for each + E.G
Eukaryotes : Has Extron and introns, Long, linear and histones, chromosomes,80S ribosomes E.G mitochondria/chloroplast
Prokaryotes: Only has Extron’s, short, circular and no histones, no chromosomes, 70S ribosomes - E.G plasmids
Before mitosis comes the cell cycle. What makes the cell cycle?
G1 phase / checkpoint, S phase, G2 phase / checkpoint. If bad then G0
What happens in the G1 phase / checkpoint
Phase : Organelles replicate and cell grows in size
Checkpoint : Checks size, organelle and DNA damage, if fail sent to G0 to prevent further division and harm
What happens in the S phase?
DNA replicates its self
What happens in the G2 phase / checkpoint
phase : Further growth/protein synthesis
checkpoint : checks DNA damage, cell size and complete replication
What is mitosis and its purpose?
growth and repair. Cells divide once to produce 2 genetically identical daughter cells
Mitosis: What happens in Prophase
chromosomes condense to chromatic (2 sister chromatids)
nuclear envelope breaks down
Mitosis: What happens in Metaphase
Chromosomes line up at equator via spindle fibres attached to their centromeres
Mitosis: What happens in Anaphase
Spindle fibres shorten, chromatids r pulled to opposite poles
Mitosis: What happens in Telophase
Tele deez nuts
Nuclear envelope forms around each chromatid and chromosomes decondense into chromatids
How does DNA replication happen? (3) - Break float poly
1) DNA helicase breaks H-bonds in-between complementary base pairs (splits and exposes the strand and bases
2) New floating DNA nucleotides form H-Bonds to the exposed bases
3)DNA polymerase joins nucleotides via condensation forming phosphodiester bonds (continues to happen until a new nucleotide is formed)
What is Meiosis and its purpose?
Produce gametes for sexual reproduction. Cells divide twice and it produces 4 genetically different haploid cells
What happens in meiosis 1?
prophase I : Homologues chromosomes pair up and nuclear envelope breaks down
Metaphase I : homologous pairs line up at equator
Anaphase I : Homologues chromosomes are pulled to opposite poles via spindle fibres
Telophase I : chromosomes decondense and nuclear envelope forms around each group
What happens is meiosis 2?
Diff cuz starts w hapolid
Prophase II : chromatin recondenses into 23 chromosomes
Metaphase II : Chromosomes r lined up at the equator
Anaphase II : Sister chromatids are pulled to opposite poled via spindle fibres
Telophase II : Decondenses to chromatin and nuclear envelope forms around each group
How does meiosis contribute to genetic variation? (2)
1) different combos as independent assortment in metaphase I when the homologous pair randomly line up in the equator of the cell
2)Crossing over and chromosomes twisting around each other causing portions to exchange in Prophase I