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Flashcards in DNA is heritable material Deck (22):
1

In 1928, he was credited with recognizing TRANSFORMATION in bacteria.

Frederick Griffith

2

In what year did Griffith discover the pneumoniae shit?

1928

3

Disease-causing (pathogenic) baterium causing pneumonia

Streptococcus pneumoniae

4

The _____ is a virulence factor.

Capsule

5

What are the 2 strains of streptococcus?

1. Pathogenic (capsule; virulent) S-strain
2. Non-pathogenic (capsule-free; non-virulent) R-strain

6

What is pathogenic strain?

S-strain

7

What is non-pathogenic strain?

R-strain

8

Griffith’s conclusion?

Transformation adds new pieces of genes to live bacterial cells

9

The transfer of information is called ___.

Transformation

10

Transforming bacteria nowadays is to insert foreign DNA into bacteria to allow microbe to produce molecule like ______ & ______.

Human growth hormone
Human insulin

11

Two macromolecules became candidates for genetic material when it was shoed that genes were located on chromosomes. What are they?

DNA (4 different monomers)
Protein (20 different monomers)

12

When did Avery, MacLeod, & McCarty repeat Griffith' experiment?

1944

13

In 1944, Griffith's experiemtn was repeated by whom?

Avery, MacLeod, & McCarty

14

What did Avery, MacLeod, & McCarty discover?

degradation of protein did not destroy its ability to transform Rstrain cells but degraded DNA destruyed all transforming ability

15

What is Avery, MacLeod, & McCarty's conclusion?

The molecule that carries the heritable information is DNA.

16

In what year did Hershey and Chase did their discovery?

1952

17

What did Hershey and Chase discover?

performed experiments showing that DNA is the genetic material of a phage known as T2 with blender experiment

18

Viruses that infect bacteria.

Bacteriophage

19

What composes bacteriophage?

DNA packed inside head and protein making up the outer coat

20

How to distinguish DNA from protein?

Protein: some amino acids contain sulfur,but NEVER phosphorous

DNA: have phosphorous , but NEVER sulfur

21

Only the bacteriophage ____ entered the bacteria

DNA

22

What is Hershey and Chase's conclusion?

DNA is the genetic material since radioactive DNA ended up in viral offsrping