Flashcards in Drug interactions Deck (17):
What antibiotics interact with theophylline?
Macrolides eg arithromycin, clarithromycin
What two rugs interact with macrolide antibitoics?
What do ACE inhibitors do with respect to sulfonylureas?
Increase hypoglycaemic effect.
What pathway does gradefuit juice block? What drug does this effect?
Cytochrome P450. Interferes with statins - causes more muscle aches.
What medicine does st johns wort interfere with?
Oral contraceptive pill.
What is a type A drug reaction?
Augmented pharmacologic effects
- dose dependent and predictable
What is a type B reaction?
Bizarre effects (or idiosyncratic) -
dose independent and unpredictable
What is a type C reaction?
What is a type D reaction?
What is a type E reaction?
End of treatment effects.
What is a type F reaction?
Failure of treatment
What condition can long term treatment with beta blockers cause?
What condition an long term treatment with NSAIDS cause?
What is important management in type C treatment?
What does abrupt stopping of beta blockers cause?
What biochemical symptoms do yu get in an addisonian crisis?