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Flashcards in Drug interactions Deck (17):
1

What antibiotics interact with theophylline?

Macrolides eg arithromycin, clarithromycin

2

What two rugs interact with macrolide antibitoics?

Stantins
Theophylline

3

What do ACE inhibitors do with respect to sulfonylureas?

Increase hypoglycaemic effect.

4

What pathway does gradefuit juice block? What drug does this effect?

Cytochrome P450. Interferes with statins - causes more muscle aches.

5

What medicine does st johns wort interfere with?

Oral contraceptive pill.

6

What is a type A drug reaction?

Augmented pharmacologic effects
- dose dependent and predictable

7

What is a type B reaction?

Bizarre effects (or idiosyncratic) -
dose independent and unpredictable

8

What is a type C reaction?

Chronic effects

9

What is a type D reaction?

Delayed effects

10

What is a type E reaction?

End of treatment effects.

11

What is a type F reaction?

Failure of treatment

12

What condition can long term treatment with beta blockers cause?

Diabetes

13

What condition an long term treatment with NSAIDS cause?

Hypertension

14

What is important management in type C treatment?

Monitoring

15

What does abrupt stopping of beta blockers cause?

Angina

16

What biochemical symptoms do yu get in an addisonian crisis?

High pottassium
(Low sodium)
Hypotension
Unwell
Pigmentation

17

What can cause an addisonian crisis?

Removal of steroids