Endocrine Disrupting Compounds - Final Exam Flashcards
(20 cards)
EDC
Endocrine disrupting compounds
What can EDC have an effect on? (3)
- Health
- Growth
- Reproduction
What are 7 types of EDC?
- Pesticides, herbicides, fungicides
- Polyaromatic compounds
- Organic oxygen compounds
- Surfactants
- Drugs
- Metals
- Phytoestrogens
What it bisphenol A used in the manufacture of?
Some clear plastics
What are 2 examples that bisphenol A is made in?
- Baby feeding bottles
2. Lines most tin cans
What does bisphenol A bind to?
GPCR30
What potency does phthalates have compared to 17beta-estradiol?
6-7x less potency
- weakly estrogenic
What does phthalates do to plastic?
Makes them bendier
BPA
Bisphenol A
What does bisphenol A have an effect on? (2)
- Reproductive organs
2. Daily sperm production
What is the unique/ unusual problem about bisphenol A?
That it causes problems at both high and low doses
What does BPA do that was discovered in mice but have the same effect in humans?
Found to have insulin resistance
DES
Diethylstilbestrol
What is diethylstilbestrol used in?
Crystallization elements
What are 2 examples of isoflavones?
- Soybeans
2. Legumes
What are 2 things isoflavones may do?
- Impede sexual maturation of boys
2. Accelerate sexual maturation of girls
What does a soy-fed baby receive daily?
Increase in estrogen
CAFIA
Czech agriculture and food inspection authority
What are 2 supplements that are under analysis for being banned for sportsmen?
- Creatine
2. Pyruvate
What are 2 banned anabolic steroids?
- 19-norandrostenedione
2. Androstenedione
