endocrine histology Flashcards
(39 cards)
what connects pituitary gland to hypothalamus
infundibulum
what is proper name for ant. pituitary
adenohypophysis
3 types of cell in adenohypophyissi histology
chromophobes 50%
acidophils 40%
basophils 10%
what are Herring bodies
axon bulgings, containing secretory granules, spheroid, eosinophilic
what is name for post. pituitary
neurohypophysis
adenoma histology in pituitary
monotonous pattern, uniform cells
most comon adenomas in anterior pituitary
lactotroph amd somatotroph
which cells produce parathyroid hormone
chief
functional unit of the thyroid
follicle
what cells are in between thyroid follices
C (clear) cell
what is in colloid
iodinated thyroglubulin
what is t4
thyroxine
what do Clear cells secrete
calcitonin
normal morphology of thyroid follicular epithelial cells
cuboidal or low columnar
Graves disease histology
Diffuse hypertrophy and hyperplasia of follicular cells (tall and columnar and more crowded) —results in papillary formation which project into the lumen.
Lymphoid infiltration (mostly T cells) into the thyroid stroma
Cells often are enlarged and can show cytoplasmic eosinophilia, with enlarged nuclei and can mimic the nuclei of papillary thyroid carcinoma (no fibrovascular cores)
The colloid shows scalloping reflecting increased use of the colloid to produce thyroxin
hashimoto antigen against
follicular cells
moprhology of hashimoto
eosinophilic epithelial Hurthle cells (big, granular, oncocytes) and fibrotic bands.
goitre?
graves
Hashimoto BUT eventually atrophy
scalloping Graves disease, colloid is atrophied
which is widest zona in adrenal gland
fasciculat
chromaffin cells are called becuase
stain with chromium
origin of chromaffin cells
neurones
where are chromaffin cells
adrenal medulla