endocrine histology Flashcards

(39 cards)

1
Q

what connects pituitary gland to hypothalamus

A

infundibulum

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2
Q

what is proper name for ant. pituitary

A

adenohypophysis

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3
Q

3 types of cell in adenohypophyissi histology

A

chromophobes 50%
acidophils 40%
basophils 10%

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4
Q

what are Herring bodies

A

axon bulgings, containing secretory granules, spheroid, eosinophilic

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5
Q

what is name for post. pituitary

A

neurohypophysis

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6
Q

adenoma histology in pituitary

A

monotonous pattern, uniform cells

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7
Q

most comon adenomas in anterior pituitary

A

lactotroph amd somatotroph

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8
Q

which cells produce parathyroid hormone

A

chief

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9
Q

functional unit of the thyroid

A

follicle

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10
Q

what cells are in between thyroid follices

A

C (clear) cell

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11
Q

what is in colloid

A

iodinated thyroglubulin

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12
Q

what is t4

A

thyroxine

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13
Q

what do Clear cells secrete

A

calcitonin

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14
Q

normal morphology of thyroid follicular epithelial cells

A

cuboidal or low columnar

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15
Q

Graves disease histology

A

Diffuse hypertrophy and hyperplasia of follicular cells (tall and columnar and more crowded) —results in papillary formation which project into the lumen.

Lymphoid infiltration (mostly T cells) into the thyroid stroma

Cells often are enlarged and can show cytoplasmic eosinophilia, with enlarged nuclei and can mimic the nuclei of papillary thyroid carcinoma (no fibrovascular cores)

The colloid shows scalloping reflecting increased use of the colloid to produce thyroxin

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16
Q

hashimoto antigen against

A

follicular cells

17
Q

moprhology of hashimoto

A

eosinophilic epithelial Hurthle cells (big, granular, oncocytes) and fibrotic bands.

18
Q

goitre?

A

graves
Hashimoto BUT eventually atrophy

19
Q
A

scalloping Graves disease, colloid is atrophied

20
Q

which is widest zona in adrenal gland

22
Q

chromaffin cells are called becuase

A

stain with chromium

23
Q

origin of chromaffin cells

24
Q

where are chromaffin cells

A

adrenal medulla

25
chromaffin cells produce
adrenaline
26
functional adenomas in adrenal cortex cause
Cushings
27
stimulants (2) of ZG
K levels and angiotensin 2
28
difference between Cushings syndrom and disease
???
29
ZF cells are filled with
lipid droplets
30
what is addisons disease
autoimmune adrenal hypofunction degeneration of the cortex
31
histopathology of addisons
Atrophic glands Fibrosis of adrenal capsule No differentiation of the cortical epithelial areas and the medulla (below) Marked lymphocytic infiltration (autoimmune)
32
pheocromocytoma means
dark colour tumour
33
pheochromocytoma location
medulla
34
Symptoms of hyperthyroidism
High blood pressure, Headache, Heavy sweating, Rapid heartbeat, Tremors Pallor, Shortness of breath Panic attack-type symptoms
35
exocrine pancreas produces
digestive enzyems
36
endocrine pancreas prodyces
insulin glucagon pancreatic polypeptides
37
histopathology DMt1
shrunken and fewer islets
38
DT2 what can you see
amyloid deposits
39