kidney development Flashcards
embryological origin of kidneys
intermediate mesoderm
what else other than kidneys is made from intermediate mesoderm
gonads
mullerian ducts
wolffian ducts
urinary system
mesonephric duct is called
wolffian
paramesonephric is called
mullerian
in the female, the mesonephric duct….
almost completely degrades, just the lower part becomes the ureteric bud
in the female, the mullerian ducts become…
oviducts
in the male, the mesonephric duct….
forms the ureteric bud and the male reproductive system
in the male, the paramesonephric duct…
degenerates
the ureteric bud is developed from… and forms…
mesonephric ducts
collecting system - collecting tubules, ureter, major and minor calyces
how many embryological kidneys are there and what is the important one
3
metanephric (not mesonephric)
ureteriic bud comes into contact with what to form kidney
mesenchyme (from mesoderm)
how many collecting tubules in the kidney
1-3 million
what does the first bifurcation of the ureteric bud form
major calyces
kidney blastema (metanephric bud) becomes
excretory part of kidney - glomerulus, bowman’s capsule, pct, loop of henle, dct
where does embryological kidney move from and to
s1-t12
why kidney agenesis
failure of ureteric bud to meet the mesenchymal tissue so kidney doesn’t decelop
unilateral kidney agenesis incidence
1/1000
bilateral kidney agenesis consequences
poor lung development, baby will survive in utero but not after birth
what is oligohydramnios
not enough amniotic fluid
bifid ureter, a problem?
no
what is it called if both poles of teh kidneys fuse
pancake kidney
where does horseshoe kidney get stucl
IMA
horseshoe kidney incidence
1/500
mutations in which proteins cause polycystic kidneys and which modes of inheritance also what goes wrong
polycystin
AD
problems with primary cilia
