insulin Flashcards

1
Q

glucagon is a…

A

insulin counter-regulatory hormone

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2
Q

how many aa inglucagon

A

29

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3
Q

what is glucagon stored as

A

pro-glucagon

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4
Q

what other than glucagon is made from pro-glucagon

A

glp-1

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5
Q

which aa’s in blood increase glucagon secretion

A

alanine and arginine

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6
Q

glucagon receptor

A

gpcr

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7
Q

insulin receptor

A

tyrosine kinase

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8
Q

glucagon binding pathway

A
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9
Q

glucagon stimulates what in the liver (2)

A

glycogenolysis
gluconeogenesis

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10
Q

PKA stimulates… and inhibits (enzymes)

A

glycogen phosphorylase

glycogen synthase

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11
Q

in the liver, glucagon

A

inhibits glycolysis and increases gluconeogenesis

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12
Q

excess acetyl coa is turned into

A

ketone bodiessss

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13
Q

what are the 2 main ketone bodies

A

acetone
beta hydroxybutarate

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14
Q

adrenaline in fasting where does it go what does it do

A

goes to muscle, stimulates glycogen olysis via cAMP activating PKA

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15
Q

where is GLP1 produced

A

L cells - enteroendocrine cells - ileo-colonic

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16
Q

GLP1 is cleaved by

A

DPP4