Endocrine Review Flashcards

(47 cards)

1
Q

Most common endocrinopathy of older cats

A

HyperT

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2
Q

Young-mid age FEMALE dogs most often affected

A

Hypoadrenocorticism

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3
Q

Addison’s

A

Hypoadrenocorticism

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4
Q

Occurs in middle aged med/lg breed dogs

A

HypoT

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5
Q

Occurs in mid-older (avg 12yo) dogs and rarely in cats

A

Hyperadrenocorticism

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6
Q

Cushing’s

A

Hyperadrenocorticism

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7
Q

Most commonly diagnosed in 7-10yo dogs but also common in cats

A

Hyperglycemia

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8
Q

Diabetes mellitus

A

Hyperglycemia

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9
Q

Clinical signs of this imbalance are only seen when severe

A

HypoCa

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10
Q

Causes PU/PD, inappetance and V/D, and dystrophic mineralization

A

HyperCa

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11
Q

Idiopathic form of this disease is rare but occurs mostly in small breed female dogs

A

Primary hypoCa

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12
Q

What is the most common cause of hypoCa?

A

Iatrogenic (post-thyroidectomy)

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13
Q

Puerperal tetany aka milk fever occurs more often in what breed of dogs?

A

Small breeds

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14
Q

How does the body respond to a minor decrease in Ca?

A

Increases PTH

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15
Q

How does the body respond to a major drop in Ca?

A

Increases PTH and Vit D3

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16
Q

What are the only diseases that cause hypoCa severe enough for clinical signs?

A

Eclampsia and hypoPTH

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17
Q

How can you ddx eclampsia from hypoPTH?

A

Phosphorus will be increased w/hypoPTH

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18
Q

How is an ECG affected by hypoCa?

A

Deep, wide T-waves

Prolonged Q-T and S-T intervals

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19
Q

How do you treat hypoCa?

A

IV Ca gluconate

20
Q

How can you treat hyperCa?

A

Saline duresis, furosemide, calcitonin

21
Q

What are the main systems of the body affected by hypoT?

A

Weight, attitude, skin and coat

22
Q

Rough, thin coat, rat tail, seborrhea

23
Q

What endocrine disease causes myxedema?

24
Q

Deposition of mucopolysaccharides in the dermis

25
Scraggly, unkempt coat, weight loss, thyroid slip, PU/PD, GI signs, tachycardia, loss of facial muscle mass
HyperT
26
What is the most common cause of hyperT?
Functional tumor (adenoma)
27
What is the most common cause of hypoT?
Thyroid disease (idiopathic or lymphocytic thyroiditis)
28
2* hypoT is caused by a disease in the _____
Pituitary
29
Waxing/waning signs of ADR, dehydration, possible bradycardia
Hypoadrenocorticism (Addison's)
30
Lack of cortisol/things that control mineralocotricoids
Hypoadrenocorticism (Addison's)
31
What is atypical hypoadrenocorticism (Addison's)?
Pituitary lesion that decreases ACTH
32
How can a dog develop iatrogenic hypoadrenocortism (Addison's)?
Abrupt discontinuation of steroids w/o time for atrophied adrenal glands to respond
33
What is the precursor of aldosterone and cortisol (and androgens)?
Cholestrol
34
How will hypoadrenocorticism (Addison's) affect and ECG?
Bradycardia w/absent P-wave and spiked T-wave
35
What biochemistry panel is most commonly elevated in cats with hyperT?
ALT
36
What biochemistry parameters allow you to make a presumptive hypoT dx?
Low T4 + high TSH
37
How do you test for hyperT?
T4 or fT4 eqd
38
How do you treat hypoT?
Levothyroxine, Soloxine or Leventa
39
Why are hyperT cats more prone to UTI?
Dilute urine promotes bacterial growth
40
What % of thyroid tumors are bilateral?
70%
41
How do you treat hyperT?
30d methimazole + I-131
42
Will you see a stress leukogram with hypoadrenocorticism (Addison's)? Why or why not?
No b/c no cortisol to cause it
43
Azotemia, hypoNa, and hyperK can indicate what endocrine disaease?
Hypoadrenocorticism (Addison's)
44
How do you treat hypoadrenocorticism?
Dexmethasone, fluids, maintenance steroids
45
Patients with atypical Addison's only require which steroid supplementation?
Glucocorticoids
46
What fluid therapy is used to restore blood volume and treat hyperK associated with hypoadrenocorticism (Addison's)?
NaCl + Ca gluconate/dextrose
47
What will an ACTH stim test result be in an animal with hypoadrenocorticism (Addison's)?
Flat line