Clin Path Review 4 Flashcards

1
Q

When does a regenerative anemia d/t blood loss NOT have normal RBC morphology?

A

Hemangiosarcoma in dogs

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2
Q

Does blood loss cause thrombocyotopenia?

A

NO NO NO

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3
Q

What is the most common way in which blood is chronically lost?

A

Via intestine

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4
Q

Microcytosis, keratocytes, regenerative anemia, low serum iron

A

Iron deficiency anemia

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5
Q

How will iron storage differ with anemia of inflammatory disease?

A

High serum iron

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6
Q

What causes extravascular hemolysis?

A

Phagocytosis of RBCs in spleen, liver, etc

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7
Q

What diseases cause extravascular hemolysis?

A

IMHA, heinz body anemia, RBC parasites, hypophosphatemia

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8
Q

What are signs of blood destruction?

A

Anemia, splenomegaly, normal TP

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9
Q

IMHA is assoc. w/what in horses?

A

Penicillin, Clostridium, neoplasia

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10
Q

IMHA is assoc. w/what in cats?

A

Mycoplasma, FeLV, neoplasia

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11
Q

Which dog breed is at highest risk for IMHA?

A

Cocker spaniels

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12
Q

Thrombocytopenia, inflammatory leukogram, azotemia, Spherocytes

A

IMHA

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13
Q

Spherocytes can be seen in horses with what infection?

A

Clostridial infections

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14
Q

What do IMHA animals usually die of?

A

Thromboembolism

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15
Q

How do you treat IMHA?

A

Glucocorticosteroids, fluids

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16
Q

Direct antiglobulin test done to detect IMHA as long as agglutination is not present

A

Coomb’s test

17
Q

Maternal antibodies against neonate’s blood group antigen

A

Neonatal isoerythrolysis

18
Q

Which erythrocyte parasites cause intravascular hemolysis?

A

Babesia and Theileria

19
Q

Common, serous cause of severe anemia in cats that is transmitted horizontally and vertically

A

Mycoplasma haemofelis

20
Q

How do you treat Mycoplasma haemofelis infection?

A

Doxycycline for 3 weeks

21
Q

Causes severe anemia in baby pigs and is assoc. w/poor weight gain in adult pigs

A

Mycoplasma haemosuis

22
Q

How do you treat baby pigs with M. haemosuis?

A

Long-acting oxytetracycline

23
Q

Tick-borne rickettsial infection that can cause fatal hemolytic anemia d/t immune-mediated destruction

A

Anaplasmosis

24
Q

Causes severe disease and hemolytic anemia and is commonly mistaken for IMHA

A

Babesiosis

25
How do you treat Babesiosis?
Imidocarb disproprionate
26
Protozoans that cause hemolytic anemia in ruminants
Theileriosis
27
Piroplasm lives in RBCs of ruminants
Theileriosis
28
Protozoan of cats transmitted by ticks and almost always fatal
Feline cytauxzoonosis
29
What stain will dx heinz body anemia?
Wright's stain and New Methlyne Blue stain
30
Moth ball ingestion causes what type of anemia?
Heinz body anemia
31
How do you treat methemoglobinemia?
Methylene blue
32
Caused by red maple leaf ingestion in horses and nitrite poisoning in cows
Methemoglobinemia
33
Causes postparturient hemoglobinuria in cattle, DM in cats
Copper toxicosis
34
What causes yellow lamb disease?
C. perfringins type A
35
What causes bacillary hemoglobinuria and red water disease in cattle?
C. haemolyticum
36
English springer spaniels can have an autosomal recessive genetic disorder causing _____ deficiency that causes hemolytic anemia
Phosphofrutokinase
37
What dog breeds are genetically predisposed to pyruvate kinase deficiency?
Basenji, beagle, westie, Carin terriers
38
What cat breeds are genetically predisposed to pyruvate kinase deficiency?
Abyssinian, Somali, DSH