Endocrinology Flashcards Preview

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Flashcards in Endocrinology Deck (29):
1

DM1 antibodies

-anti glutamic acid decarboxylase
-anti Zn transporter
-antiinsulin
-anti-islet

2

inital fluid for DKA and HHS

NS, add 5% dextrose to fluid once glucose

3

single best screening of thyroid diseas

TSH

4

antythyroidal drugs allowed in Pregnancy

Propilthiouracyl

5

increase Thyroid binding globin states

pregnancy
estrogen administration
infection

6

thyroid neoplasm associated with MEN 2A and MEN2B

medullary thyroid carcinoma( increase calcitonin)

7

osteoporosis deifnition

-2.5 SD on DEXA

8

hyperthyroidims DDx

-graves disease
-toxic multinodular goiter
-toxic adenoma
-thyroiditis
-exogenous thyroid hormone

9

Hypothyroidism DDx

-hashimoto disease
-thyroiditis-
-secondary hypothyroidism
-congenital Hypothyroidism

10

acromegaly best initial test

IGF-1 leves

11

DI inital test

water deprivation test

12

MEN1

pancreas
pituitary
parathyroid

13

MEN2A

phochromocytoma
parathyroid
thyrois( medullary carcinoma)

14

MEN2B

thyroid(medullary carcinoma)
phochromocytoma
neuromas

15

Hb A1c goal in DM

less than 7

16

bicarb indication in DKA

PH less than 7.2

17

best initial test for acromegaly

IGF-1 levels
-the most accurate is glucose suppression test.

18

what to do when patinet has a nodule

THS and T4 if it normal do a fine-needle aspirate

19

best initial test for precense of hypercortisolism ...

24h urine cortisol

20

fatigue ,hyponatremia and hyperkalemia with hyperpigmentation

chronic hypoaldosteronism

21

best initial test for acute adreanl crisis

cosintropin test( do not rise leves)

22

hypertention + hypokalemia

primary hyperaldosteronism
do a plasma aldosterone/plasma renin ratio
most accurate test is: venous blood graining the adreanl

23

DM drugs and weight associations
-metformine
-sulfanylureas
-DPPIV inhibitors(gliptins)
-incretins
SGLT2(flozin)

-metformine=loss
-sulfanylureas= gain
-DPPIV inhibitors(gliptins)= NEUTRAL
-incretins= loss
SGLT2(flozin)=loss

24

most accurate severity measure in DKA

low bicarb

25

health maintenance in DM

statins( go below 100 on LDL)
ACEIS or ARBS( for microalbuminuria)
yearly eye and foot examintion
ASA everyone >30 years old

26

most common cause of death in acromegaly

CHF

27

antithyroid peroxidase Ab

if positive give thyroid replacement

28

best initial therapy for gaves opthalmopaty

Steroids

29

fatigue, hyponatremia , hyperkalemia with HYPERPGIMENTATION

Hyperpigmentation means Chronic adreanl insufficiency