Endocrinology

Question 1

DM1 antibodies

Answer 1

• anti glutamic acid decarboxylase
• anti Zn transporter
• antiinsulin
• anti-islet

Question 2

inital fluid for DKA and HHS

Answer 2

NS, add 5% dextrose to fluid once glucose

Question 3

single best screening of thyroid diseas

Answer 3

TSH

Question 4

antythyroidal drugs allowed in Pregnancy

Answer 4

Propilthiouracyl

Question 5

increase Thyroid binding globin states

Answer 5

pregnancy
estrogen administration
infection

Question 6

thyroid neoplasm associated with MEN 2A and MEN2B

Answer 6

medullary thyroid carcinoma( increase calcitonin)

Question 7

osteoporosis deifnition

Answer 7

-2.5 SD on DEXA

Question 8

hyperthyroidims DDx

Answer 8

• graves disease
• toxic multinodular goiter
• toxic adenoma
• thyroiditis
• exogenous thyroid hormone

Question 9

Hypothyroidism DDx

Answer 9

• hashimoto disease
• thyroiditis-
• secondary hypothyroidism
• congenital Hypothyroidism

Question 10

acromegaly best initial test

Answer 10

IGF-1 leves

Question 11

DI inital test

Answer 11

water deprivation test

Question 12

MEN1

Answer 12

pancreas
pituitary
parathyroid

Question 13

MEN2A

Answer 13

phochromocytoma
parathyroid
thyrois( medullary carcinoma)

Question 14

MEN2B

Answer 14

thyroid(medullary carcinoma)
phochromocytoma
neuromas

Question 15

Hb A1c goal in DM

Answer 15

less than 7

Question 16

bicarb indication in DKA

Answer 16

PH less than 7.2

Question 17

best initial test for acromegaly

Answer 17

IGF-1 levels

-the most accurate is glucose suppression test.

Question 18

what to do when patinet has a nodule

Answer 18

THS and T4 if it normal do a fine-needle aspirate

Question 19

best initial test for precense of hypercortisolism …

Answer 19

24h urine cortisol

Question 20

fatigue ,hyponatremia and hyperkalemia with hyperpigmentation

Answer 20

chronic hypoaldosteronism

Question 21

best initial test for acute adreanl crisis

Answer 21

cosintropin test( do not rise leves)

Question 22

hypertention + hypokalemia

Answer 22

primary hyperaldosteronism
do a plasma aldosterone/plasma renin ratio
most accurate test is: venous blood graining the adreanl

Question 23

DM drugs and weight associations
-metformine
-sulfanylureas
-DPPIV inhibitors(gliptins)
-incretins
SGLT2(flozin)

Answer 23

-metformine=loss
-sulfanylureas= gain
-DPPIV inhibitors(gliptins)= NEUTRAL
-incretins= loss
SGLT2(flozin)=loss

Question 24

most accurate severity measure in DKA

Answer 24

low bicarb

Question 25

health maintenance in DM

Answer 25

statins( go below 100 on LDL) ACEIS or ARBS( for microalbuminuria) yearly eye and foot examintion ASA everyone >30 years old

Question 26

most common cause of death in acromegaly

Answer 26

CHF

Question 27

antithyroid peroxidase Ab

Answer 27

if positive give thyroid replacement

Question 28

best initial therapy for gaves opthalmopaty

Answer 28

Steroids

Question 29

fatigue, hyponatremia , hyperkalemia with HYPERPGIMENTATION

Answer 29

Hyperpigmentation means Chronic adreanl insufficiency