Flashcards in Endocrinology Deck (29):
1
DM1 antibodies
-anti glutamic acid decarboxylase
-anti Zn transporter
-antiinsulin
-anti-islet
2
inital fluid for DKA and HHS
NS, add 5% dextrose to fluid once glucose
3
single best screening of thyroid diseas
TSH
4
antythyroidal drugs allowed in Pregnancy
Propilthiouracyl
5
increase Thyroid binding globin states
pregnancy
estrogen administration
infection
6
thyroid neoplasm associated with MEN 2A and MEN2B
medullary thyroid carcinoma( increase calcitonin)
7
osteoporosis deifnition
-2.5 SD on DEXA
8
hyperthyroidims DDx
-graves disease
-toxic multinodular goiter
-toxic adenoma
-thyroiditis
-exogenous thyroid hormone
9
Hypothyroidism DDx
-hashimoto disease
-thyroiditis-
-secondary hypothyroidism
-congenital Hypothyroidism
10
acromegaly best initial test
IGF-1 leves
11
DI inital test
water deprivation test
12
MEN1
pancreas
pituitary
parathyroid
13
MEN2A
phochromocytoma
parathyroid
thyrois( medullary carcinoma)
14
MEN2B
thyroid(medullary carcinoma)
phochromocytoma
neuromas
15
Hb A1c goal in DM
less than 7
16
bicarb indication in DKA
PH less than 7.2
17
best initial test for acromegaly
IGF-1 levels
-the most accurate is glucose suppression test.
18
what to do when patinet has a nodule
THS and T4 if it normal do a fine-needle aspirate
19
best initial test for precense of hypercortisolism ...
24h urine cortisol
20
fatigue ,hyponatremia and hyperkalemia with hyperpigmentation
chronic hypoaldosteronism
21
best initial test for acute adreanl crisis
cosintropin test( do not rise leves)
22
hypertention + hypokalemia
primary hyperaldosteronism
do a plasma aldosterone/plasma renin ratio
most accurate test is: venous blood graining the adreanl
23
DM drugs and weight associations
-metformine
-sulfanylureas
-DPPIV inhibitors(gliptins)
-incretins
SGLT2(flozin)
-metformine=loss
-sulfanylureas= gain
-DPPIV inhibitors(gliptins)= NEUTRAL
-incretins= loss
SGLT2(flozin)=loss
24
most accurate severity measure in DKA
low bicarb
25
health maintenance in DM
statins( go below 100 on LDL)
ACEIS or ARBS( for microalbuminuria)
yearly eye and foot examintion
ASA everyone >30 years old
26
most common cause of death in acromegaly
CHF
27
antithyroid peroxidase Ab
if positive give thyroid replacement
28
best initial therapy for gaves opthalmopaty
Steroids
29