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Flashcards in Endocrinology Deck (228)
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1

Prehormone syntheiss occurs in the __________ and is directed by a specific mRNA

endoplasmic reticulum

2

__________ are cleaved from prehormone. producing prohormone, which is transported to the Golgi apparatus

Signal peptides

3

Addtional peptide sequences are cleaved in the golgo apparatus to form the _________, which is packaged in secretory granules for later release

Hormone

4

Steroid hormones are derivatives of _____________ 

Cholesterol

5

Amine hormones (Thyroid hormones, epinephrine, norepinephrine) are derivatives of ___________

tyrosine

6

Most commonly applied principle for regulating hormone secretion

self limiting

Negative feedback

7

Explosive and self reinforcing regulating principle of hormone secretion

Positive feedback

8

Stimulates secretion of TSH and prolactin

Thytotropin releasing hormone (TRH)

hypothalamus

9

Stimulates secretion of ACTH

CRH

hypothalamus

10

Stimulates secretion of LH and FSH

GnRH

11

Stimulates secretion of growth hormone

GHRH

Hypothalamus

12

Inhibits secretion of growth hormone

Somatotropin release-inhibiting hormone (Somatostain)

Hypothalamus

13

Inhibits secretion of prolactin

Prolactin-inhibiting hormone (dopamine)

hypothalamus

14

Stimulates synthesis and secretion of thyroid hormones

TSH

anterior pituitary

15

Stimualtes growth of ovarian follicles and estrogen secretion.

Promotoes sperm maturation (testes)

FSH

anterior pituitary

16

Stimulates ovulation, formation of corpus luteum, and synthesis of estrogen and progesterone (Ovary)

Stimualtes synthesis and secretion of testosterone (testes)

LH

Anterior pituitary

17

Stimualtes protein synthesis and overall growth

GH

anterior pituitary

18

Stimulates milk production and breast development

Prolactin

anterior pituitary

19

Stimulates synthesis and secretion of adrenal cortical hormones

ACTH

anterior pituitary

20

stimulates the synthesis and secretion of adrenal cortical hormones

ACTH

Anterior pituitary

21

Stimulates melanin synthesis

MSH

Anterior pituitary

22

Milk ejection, uterine contraction

OXytocin

posterior pituitary

23

Stimulates water reabsorption by renal collecting ducts and contraction of arterioles

ADH

Posterior pituitary

24

Skeletal growth; increase oxygen comsumption, heat production, increase protein, fat and CHO use; maturation of nervous system (perinatal)

L-Thyroxine

Triiodothyronine

 

Thyroid gland

25

Stimualtes gluconeogenesis; antiinflammatory; immunosuppression

Glucocorticoids

adrenal cortex

26

Growth and development of female reproductive organs; follicular phase of menstrual cycle

Estradiol

Ovary

27

Luteal phase of menstrual cycle

Progesterone

Ovary

28

Spermatogenesis; male secondary sex characteristics

testosterone

Testes

29

Increase serum calcium, decrease serum phosphate

PTH

parathyroid gland

30

Decrease serum calcium

Calcitonin

Thyroid gland (parafollicular cells)