Epilepsy / Local Anesthetics Flashcards Preview

Pharmacology Test II > Epilepsy / Local Anesthetics > Flashcards

Flashcards in Epilepsy / Local Anesthetics Deck (27):
1

What drugs:

decrease cortical activity → decrease seizure

teratogenic risks

epilepsy drugs

carbamazepine
ethosuximide
valproate
lorazepam

2

What epilepsy drug:

blocks Na
P450 inducer
diplopia
drowsiness
bipolar
partial complex

carbamazepine

3

What epilepsy drug:

partial complex
increase metabolism of other drugs
3A4*1B
 

carbemazepine

4

What epilepsy drug blocks Ca?

ethosuximide

5

What epilepsy drug:

no plasma binding
T1/2 = 40-60 hours

ethosuximide

6

What is the drug of choice for absence epilepsy?

ethosuximide

7

What drug:

blocks GABA and Na
 

valproate

8

What drug:

hepatotoxicity for children < 2
also for bipolar/migraines

valproate

9

What drug:

GABA inhibitor for treatment of epilepsy?

lorazepam

10

What is the degeneration of dopamine neurons?

Parkinson

11

What are the top treatments for Parkinson's?

 replace L-dopa with Sinemet

bromocryptine

selegiline

12

What is Sinemet?

L-dopa + carbidopa

13

What drug:

direct activation of dopamine receptors

bromocryptine

14

What drug:

blocks dopamine metabolism by MAO-B

selegiline

15

For LA, what type fibers are fastest to slowest to be affected?

Type C>B>A

16

What is the mechanism of action for LAs?

voltage gated Na blocker

17

What is the order of blockade for the following senses/functions?

Touch

Pain

Deep pressure

Cold

Motor

Pain  > Cold > Touch > Deep Pressure >  Motor

 

18

What class of LA is safer due to shorter half life?

esters

19

What LA:

PABA blocks sufonamide
used for infiltration and regional anesthesia

Procaine

20

What LA:

is used topically

benzocaine

short acting ester

21

What LA is:

intermediate acting
risk of increased toxicity among esters
 

tetracaine

22

What LA:

used for anesthesia for the nose/throat
cause mucous membrane irritation

tetracaine

23

What LA:

replaced cocaine for cornea anesthesia b/c less irritating

proparacaine

24

What LAs:

short-acting esters

procaine
benzocaine
tetracaine
proparacaine

25

What LAs:

amides

lidocaine
bupivicaine

26

What LA:

intermediate
use caution with amiodarone b/c causes arrhythmias
used for spinals

lidocaine

27

What LA:

used for long, regional anesthesia
epidurals with opioids in labor
can also induce arrhythmias?

bupivicaine