Exam 2 - 2009 Flashcards Preview

Pharmacology Test II > Exam 2 - 2009 > Flashcards

Flashcards in Exam 2 - 2009 Deck (16):
1

Which of the following statements about epilepsy therapies is correct?
A. The anticonvulsant action of carbamazepine (Tegreto)l involves block of T type calcium channels in cortical neurons
B. Gingival hyperplasia and hirsutism are common side effects of valproate ( Depakote)
C. Ethosuximide (zarontin) Is an effective drug for treatment of partial complex seizures
D None of the above

D. None of the above

2

Which of the following drugs directly activates mu opioid receptors?
A. Naltrexone (ReVia)
B. Disulfiram (Antabuse)
C. Naloxone (Narcan)
D. Methadone (dolophine)

D. Methadone (dolophine)

3

Which of the following drugs can reverse the coma and respiratory depression caused by morphine overdose?
A. Naloxone
B. Methadone (dolophine)
C codeine
D. Disulfiram (Antabuse)

A. Naloxone

4

Flumazenil (romazicon) Blocks the pharmacological actions of
A. Benzodiazepine
B. Non-benzodiazepine benzodiazepine receptor agonist (NBRAs)
C. Both a and B
D. Neither a nor B

C. Both a and B

4

Lithium carbonate
A. Can be used in combination with the antipsychotic drug haloperidol for the treatment of acute mania
B. Is effective in the prophylactic treatment of bipolar affective disorder decreasing both the manic and depressive phases
C. Can be used in combination with the antiepileptic drug carbamazapine for the prophylactic treatment of bipolar affective disorder
D. Has all of the above characteristics

D. Has all of the above characteristics

4

T or F. Opioid antagonists are used to relieve severe pain

F

4

T or F Direct application of morphine to the spinal cord provides a regional anesthetic effect with minimal side effects

T

4

This one is skimpy because I did not want to repeat questions

Good luck. This shit sucks!

YOUR SKIMPY YOU LAZY BUMMM

5

A potassium sparing diuretic the blocks collecting duct sodium channels thereby reducing potassium secretion into the urine that would otherwise occur when sodium delivery to the collecting duct is high
A. Furosemide (Lasix)
B. hydrochlorothiazide (hydrodiuril)
C. Acetozolamide (diamox)
D. Triameterin (dyrenium)

D. Triameterin (dyrenium)

6

A drug with very weak diuretic activity it acts in the proximal tubule to inhibit carbonic anhydrase leading to bicarbonate ion loss and the formation of an alkaline urine
A. Furosemide (Lasix)
B. hydrochlorothiazide (hydrodiuril)
C. Acetozolamide (diamox)
D. Triameterin (dyrenium)

C. Acetozolamide (diamox)

7

Inhibits in NKCC co transporters in the ascending loop of Henle and is the diuretic of choice to treat edematous conditions and other volume expanded states
A. Furosemide (Lasix)
B. hydrochlorothiazide (hydrodiuril)
C. Acetozolamide (diamox)
D. Triameterin (dyrenium)

A. Furosemide (Lasix)

8

A relatively weak diuretic that causes a long-term reduction of peripheral vascular resistance and is most commonly prescribed for the treatment of hypertension
A. Furosemide (Lasix)
B. hydrochlorothiazide (hydrodiuril)
C. Acetozolamide (diamox)
D. Triameterin (dyrenium)

B. hydrochlorothiazide (hydrodiuril)

9

Which of the following statements is true about second-generation H1 receptor antagonists?
A. They are not highly selective for the H1 receptor
B. They do not cross the blood brain barrier to the levels observed with first generation H1 antagonists
C. They are the drug of choice for treating anaphylactic shock
D. They are effective in decreasing acid secretion in the stomach

B. They do not cross the blood brain barrier to the levels observed with first generation H1 antagonists

10

Infliximab is used in treating rheumatoid arthritis because...
A. It binds to the TNF Alpha receptor
B. It prevents mast cell degranulation
C. It binds to the glucocorticoid receptor
D. It binds to TNF alpha and prevents the cytokine from binding to its receptor

D. It binds to TNF alpha and prevents the cytokine from binding to its receptor

11

Cortisol
A. Is a long acting glucocorticoid
B. Has minimal salt retaining activity
C. Is characterized by both a and B
D. Is characterized by neither a nor B

D. Is characterized by neither A nor B

12

Which of the following statements is true about glucocorticoids
A. They decrease expression of Lipocortin
B. Abrupt withdrawal of glucocorticoids in patients can lead to acute adrenal insufficiency
C. All glucocorticoids bind with high affinity to the aldosterone receptor
D. No adverse effects are ever associated with long-term use

B. Abrupt withdrawal of glucocorticoids in patients can lead to acute adrenal insufficiency