Epithelia Flashcards

(65 cards)

1
Q

What are the features common to all eukaryotic cells?

A

Outer membrane, inner cytosol, cytoskeleton, membrane bound organelles and inclusions

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2
Q

What is the cytosol?

A

Solution of proteins, electrolytes and carbohydrates. Has both fluid and gel like properties

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3
Q

What is the cytoskeleton made from?

A

Thin intermediate filaments and microtubules

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4
Q

What is the function of the cytoskeleton?

A

Determines the shape and fluidity of the cell

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5
Q

Where are the membrane bound organelles?

A

In the cytosol

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6
Q

What are inclusions?

A

Other structures within the cytoplasm which may or may not be bound by a membrane

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7
Q

What has to happen to cell metabolism and degradative post mortem processes?

A

Has to be haited

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8
Q

What is fixation?

A

Cells being exposed to a chemical that prevents cell metabolism and degradative post mortem processes.

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9
Q

What is the most common fixation?

A

Formalin

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10
Q

What does formalin react with?

A

The amino groups on proteins

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11
Q

What is embedding?

A

Process where the tissue is embedded in support medium

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12
Q

What does embedding allow?

A

The tissue to be thinly sliced allowing light or electrons to penetrate the tissue

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13
Q

What is the impregnated material used to cut the tissue?

A

Paraffin wax

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14
Q

Stains are…

A

Aqueous

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15
Q

Common stains used?

A

Haematoxyoin and Eosin

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16
Q

What colour does Haematoxylin stain the nucleus?

A

Blue / purple

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17
Q

The acidic molecules in haematoxylin are said to be?

A

Basophilic

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18
Q

What kind of dye is Eosin?

A

Acidic

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19
Q

What colour does Eosin stain?

A

Pinkish red

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20
Q

Structures stain in Eosin are said to be?

A

Eosinophilic

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21
Q

What are the 4 tissue types?

A

Epithelium, connective tissue, muscle and nervous tissue

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22
Q

What does the epithelia form?

A

The secretory part of some solid organs and glands

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23
Q

What a the function of the surface epithelium?

A

Cover and lines surfaces, cavities and tubes

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24
Q

What is epithelia composed of?

A

Closely aggregated, polyhedral epithelial cells with a minimum of intercellular substance

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25
Adhesion between cells is?
Strong
26
What happens when cellular sheets are formed?
Able to cover exposed external surfaces and line internal cavities
27
Functions of epithelia?
Mechanical barrier, Chemical barrier, Absorption, Secretion, Containment and Locomotion
28
Example of mechanical barrier?
Skin
29
Example of chemical barrier?
Lining of the stomach
30
Example of absorption?
Lining of intestines
31
Example of secretion?
Salivary gland
32
Example of containment?
Lining of urinary bladder
33
Example of Locomotion?
Oviduct
34
Minor functions of epithelium include?
Sensation (taste buds) and contractility (myoepithelial cells)
35
What are the characteristics of epithelium?
Typically polarised, basal surface attached to basal lamina, non vascularised, adhere together in sheets so cells are closely apposed to each other
36
What are the three main classes of filaments?
Microfilaments, intermediate filaments and microtubules
37
Filaments are classified by?
Size
38
Size of microfilament?
5nm in diameter
39
Size of intermediate filament?
10nm in diameter
40
Size of microtubules?
25nm in diameter
41
What do the filamentous proteins become attached to?
Cell membranes and to each other
42
What is the function of intercellular junctions?
Link individual cells together into a functional unit
43
What are the 3 types of junctions?
Occluding junctions, Anchoring junctions / Adherent junctions and communicating junctions
44
What are occluding junctions?
Junctions that form a diffusion barrier
45
What are anchoring / adherent junctions?
Junctions that provide mechanical strength
46
What are communicating junctions?
Junctions that allow movement of molecules between cells
47
What is a junctions complex?
Close association of several types of junctions found in certain epithelium and other tissues
48
What are epithelia classified by?
Cell shape, number of layers, cell/tissue surface and presence of specialised cells
49
What are the cell shapes?
Squamous (flattened), cuboidal (cube shaped) and columnar (like a column)
50
What are the number of layers called?
Simple (one layer), stratified (two or more layers) and pseudostratified (tissue appears to have multiple layers, but all cells are in contact with basal lamina)
51
What are microvilli?
Finger like projections of the cell membrane
52
What are the size of microvilli?
0.5-1um in length
53
What are the function of microvilli?
Increase the surface area of the cell membrane
54
What are cilia?
Mobile cell processes
55
What is the size of cilia?
10um long
56
What is the function of cilia?
Serve to propel mucous or fluid over the cell surface
57
What is keratin?
A group of tough structural proteins.
58
Examples that are made of keratin?
Hair, fingernails and horns
59
What epithelium lines the trachea?
Pseudostratified columnar epithelium, ciliated with goblet cells
60
Where is secretion in the exocrine glands?
The apical end of the cell, into the lumen of an internal space, into a duct or onto body surface
61
The exocrine glands are termed?
Ducted glands
62
The endocrine glands are secreted?
Toward the basal end of the cell and then distributed by vascular systems throughout the body.
63
What is the endocrine gland termed?
Ductless glands
64
Examples of exocrine glands?
Lacrimal glands, salivary glands, mammary glands, liver, pancreas, brunners glands, sweat glands and sebaceous glands
65
What are examples of endocrine glands?
Pituitary glands, thyroid gland, thymus gland, pancreas, adrenal glands and ovaries/testis