Epithelium Flashcards

(74 cards)

1
Q

where are microvilli located

A
  • GI tract

- kidney

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2
Q

where are stereocilia located

A
  • epididymis

- ear cochlea

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3
Q

which apical modifications increase surface area

A
  • microvilli

- stereocilia

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4
Q

which apical modifications move substances

A

cilia

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5
Q

where are cilia located

A
  • respiratory system

- oviduct

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6
Q

what are microvilli made of

A

actin filaments

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7
Q

actin-binding proteins of microvilli

A
  • fimbrin

- fascin

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8
Q

lateral anchoring proteins of microvilli

A

myosin I

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9
Q

amorphous apex of microvilli

A

villin

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10
Q

cilia core made of

A

axoneme (9 doublets + 1 doublet microtubules)

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11
Q

what kind of arms for cilia

A

dynein arms

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12
Q

cilia function

A

transport materials along surface - beating

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13
Q

consequence of primary ciliary dyskinesia (immotile cilia)

A
  • dextrocardia
  • no mucus removal from lungs
  • infertility
  • impaired skull sinuses
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14
Q

3 cell junctions

A
  • tight (occluding) junctions
  • anchoring junctions
  • communicating (gap) junctions
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15
Q

zonula occludens type

A
  • cell to cell
  • tight junction
  • belt
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16
Q

zonula adherens

A
  • actin filaments<>actin filaments

- anchoring junction

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17
Q

macula adherens (desmosome)

A
  • intermediate filament<>intermediate filament

- anchoring junction

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18
Q

zonula occludens function

A

prevent diffusion (block paracellular pathways)

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19
Q

zolnula occuldens location

A
  • stomach (secretory)

- kidney (absorptive)

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20
Q

anchoring junctions function

A
  • stability
  • mechanical strength
  • connect cell filaments
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21
Q

zonula adherens filaments

A

actin filaments

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22
Q

zolnula adherens transmembrane link protein

A

cadherin

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23
Q

macula adherens filaments

A

intermediate filaments

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24
Q

what do intermediate filaments of macula adherens bind to?

A

intracellular plaque

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25
macula adherens transmembrane link protein
cadherin
26
pemphigus
autoimmune disease of cell junctions for middle aged patients
27
pemphigus presentation
mucous membrane blistering, widespread skin
28
pemphigus cause
desmoglein (cadherin) can't anchor the cells because antibodies for desmosomal proteins
29
2 connexons with 6 protein subunits each (connexions)
gap junctions
30
most common gap junction locations
- epithelia - cardiac and smooth muscle - embryonic tissues
31
gap junction function
transport small molecules and ions
32
basal lamina make up
- from epithelium - laminin - collagen type 4
33
reticular lamina make up
- from connective tissue | - collagen type 3
34
cell attachment connects actin filaments to basement membrane
focal adhesion
35
cell attachment connects intermediate filaments to basement membrane
hemidesmosome
36
focal adhesion peripheral protein
talin
37
focal adhesion transmembrane protein
integrin
38
hemidesmosome attachment before basement membrane
intracellular plaque
39
hemidesmosome transmembrane protein
integrin
40
which epithelium has dome cells
transitional epithelium
41
endocrine gland features
- secretion into blood/lumph (internal) - NO ducts - hormone production
42
exocrine gland features
- secretion to surface | - ducts
43
exocrine gland types
- holocrine - apocrine - merocrine
44
holocrine function
cell destruction (release whole cell) ex: Sebaceous gland
45
apocrine function
apical cytoplasm pinching (release vesicle) ex: Mammary gland
46
merocrine function
exocytosis (no cell part lost) ex: goblet cells, pancreas
47
3 types of merocrine glands
- serous - mucous - mixed
48
serous merocrine secretions
protein
49
mucous merocrine secretions
water (mucins)
50
serous gland cell structure
- active (euchromatic) nucleus - dark secretory granules - lots of ER
51
what color do serous glands stain?
dark
52
serous gland location
- pancreas | - parotid salivary gland
53
mucous glands cell structure
- inactive (heterochromatic) nucleus - pale secretory glandules - little RER
54
what color do mucous glands stain
pale
55
mucous gland function
protection and lubriction
56
mucous gland location
- Brunner's glands (stomach) | - Goblet cells (respiratory & intestine)
57
unicellular exocrine glands function
-secrete mucous
58
unicellular exocrine glands location
- goblet cells - intestine - respiratory tract
59
which type of exocrine gland is along columnar epithelial cells?
unicellular exocrine glands
60
which gland has an alveolar secretory part?
serous
61
which gland has tubular secretory part?
mucous
62
which gland has tubuloalveolar secretory part?
mixed
63
what kind of tissue for carcinoma?
barrier epithelial tissue
64
what kind of tissue for adenocarcinoma?
glandular tissue
65
what are the arms attached to doublets composed of?
dynein
66
what does a mutation in a gene encoding keratin affect?
macula adherens (desomosme)
67
what has intermediate filaments connected to basal lamina?
hemidesmosome
68
what causes a reduction in bronchial epithelium?
cilia
69
Zonula adherens actin-binding protein?
Vinculin (a-protein)
70
Zonula adherens peripheral protein?
Catenin
71
Which is a tighter link, zonula adherens or macula adherens?
Macula Adherens (desmosomes)
72
Mixed seromucous glands consist of which types of cells?
- mucous cells (tubules) | - serous cells (serous demilunes)
73
What kind of gland is the submandibular salivary gland?
mixed (seromucous) gland
74
2 types of exocrine glands
- unicellular (goblet cells) | - multicellular (mucous, serous glands)