ETOMIDATE (AMIDATE)

Question 1

CLASS

Answer 1

• HYPNOTIC

- INDUCTION AGENT

Question 2

ACTION

Answer 2

• ULTRA SHORT ACTING BENZODIAZEPINE
• NON BARBITUATE HYPNOTIC WITH NO ANALGESIC EFFECTS
• MAY HAVE GABA-LIKE EFFECTS THAT DEPRESSES THE RAS
• MINIMAL CARDIOVASCULAR AND RESPIRATORY EFFECTS
• DOES NOT RELEASE HISTAMINE

Question 3

INDICATIONS

Answer 3

FASCILITATE RSI PROTOCOLS

Question 4

PRECAUTIONS

Answer 4

• MAY CAUSE INCREASING AIRWAY RESISTANCE
• WORSENING BRONCHOSPASM IN SEVERE ASTHMA
• CARDIOVASCULAR DISEASE
• HYPOTENSION
• ELDERLY

Question 5

CONTRAINDICATIONS

Answer 5

• KNOWN HYPERSENSITIVITY TO BARBITUATES

- SHOULD NOT BE USED IN CHILDREN UNDER 10 YEARS OLD.

Question 6

ADVERSE EFFECTS

Answer 6

• MYOCLONIC/ TONIC ACTIVITY (COMMON)
• APNEA
• LARYNGOSPASMS
• HYPER/HYPO VENTILATION
• HYPER/ HYPOTENSION
• TACHY/ BRADYARRHTHMIAS
• N/V
• PAIN AT THE INJECTION SITE

Question 7

PRECAUTIONS

Answer 7

• FLUMANZE-NIL DOES NOT REVERSE ETOMIDATE

- VERAPAMIL MAY PROLONG RESPIRATORY DEPRESSION

Question 8

DOSE

Answer 8

• ADULT: 0.3mg/kg
• onset of action:: begins with 10-20 seconds.
• peaks within 1 minute and lasts for j3-5 minutes.
• PEDS: dose is the same as an adult >10 years old.