SUCCINYLCHOLINE

Question 1

CLASS

Answer 1

NEUROMUSCULAR BLOCKER (DEPOLARIZING)

Question 2

ACTIONS

Answer 2

• BINDS WITH CHOLINERGIC RECEPTORS AT THE MUSCLE MOTOR END PLATE WHICH CAUSES DEPOLARIZATION (OFTEN LEAD TO FASCICULATIONS AND SOME MUSCULAR CONTRACTIONS) AND ANTAGONIZES ACTION OF ACETYLCHOLINE TO CAUSE SKELETAL MUSCLE AND DIAPHRAGMATIC PARALYZATION.
• CAUSE RELEASE OF HISTAMINE.

Question 3

INDICATIONS

Answer 3

• FASCILITATE TRACHEAL INTUBATION- SEE PATI
• TERMINATE LARYNGOSPASM
• MUSCLE RELAXANT

Question 4

DOSAGES/ ROUTE

Answer 4

-see Hawaii adult pati protocol

• usual dose is 1.5 mg/kg rapid IV, repeat once if needed.
• IM route (PATI Protocol doubles the dose for IM route)
• Onset: less than 1 min (IV); 2-3min (IM)
• Duration: 5-10 min.

Question 5

standard prep

Answer 5

read label

Question 6

PEDIATRIC DOSE

Answer 6

USUAL DOSE IS 1-2mg/kg IV

Question 7

CONTRAINDICATIONS

Answer 7

• HX OF MALIGNANT HYPERTHERMIA
• SKELETAL MUSCLE MYOPATHIES
• AIRWAY ANATOMY MAKE INTUBATION UNLIKELY
• HYPERSENSITIVITY
• ACUTE RHABDOMYOLYSIS

Question 8

SIDE EFFECTS

Answer 8

• INITIAL MUSCLE FASCICULATION
• MALIGNANT HYPERTHERMIA
• MAY EXACERBATE HYPERKALEMIA IN POST TRAUMA INJURY, BURN PATIENTS, PATIENT WITH PARALYZED LIMB.
• EXCESSIVE SALIVATION
• HYPOTENSION
• BRADYCARDIA

Question 9

PRECAUTIONS

Answer 9

• SUCCINYLCHOLINE HAS NO EFFECT ON CONSCIOUSNESS OR PAIN.
• DURATION OF ACTION IS 4-6MIN. AND SPONTANEOUS RESPIRATIONS WILL USUALLY RESUME IN 5-10 MINUTES
• HAVE COMBITUBE, NEEDLE CRICOTHYROTOMY KIT READY AS AIRWAY ADJUNCTS IF UNABLE TO INTUBATE
• HAVE VERSED, ATROPINE, AND LIDOCAINE READY.
• MONITOR EKG, PULSE OXIMETRY, V/S, NEUROLOGICAL RESONSE