What is endosymbiosis, how does it relate to early cell
when something lives inside another thing symbiotically
organism eats another organism but its not fully digested
it can layer
leading theory for origin of euk
How to pass endosymbiosis on to the next gen`
The host eats the endosymbiot. The endosym reproduces inside
Then the host divides and takes some of the endosym with it in each divide
What is cell theory (4 things)
All things are made of cells
Cells are basic unit of struct for living things
Cell have hereditary info that is passed on
All cells come from preexisting cells - this one is not highlighted in the slids so maybe not as important?
What is central dogma of biology
DNA-> RNA-> protein
1 Replication - existing DNA become new Dna
2 transcription - new DNA makes new RNA, transcribes
3 Translation - RAN makes new proteins
what is Miller-Urey experiment
Wanted to see if in hadean conditions and inorganic things could become organic things
showed abiogenesis
2 theories on how organic molecules arise
Top down - RNA and Ribosome came first
- We know that the simplest forms of life are RNA based, so lets start there
- all life now has ribosomes
Bottom up - chemical chimera
- Look at probability and stability and see if other things are more likely
- In a computational model if you have RNA, DNA building blocks you get a more stable and realistic premise
- Its a hybrid molec of RNA and DNA
supported by recent research
Why use ribosome and RNA as beginning?
everything living now has ribosomes, found across all domains
Pure RNA can arrive abiogenetically
RNA can be genetic mat but also catalyst to make DNA, it’s a stepping stone
primary endosymbiosis versus secondary endosymbiosis
primary - when something eats another thing that stays alive inside
secondary - when the thing that has a thing inside gets eaten by another thing, likely origin of euk
Describe diagram of secondary endosymbiosis
protoeuk eats cyanobacterium, becomes plastid once it is integrated in, that is primary endosym
one of the vesicle wall surrounding the plastid is lost
first protoeuk is eaten by a bigger thing, that is secondary endosym
the first protoeuk becomes a plastid and has a vestigial nucleus
the inner ones lose genes
viral contribution to the evolution of the eukaryotic cell?
Early cells may have started as something with virus-like genetic elements?
possible that it replicated like a retrovirus?