EX3; Salivary Glands 2 Flashcards Preview

May14 Oral Histology > EX3; Salivary Glands 2 > Flashcards

Flashcards in EX3; Salivary Glands 2 Deck (64):
1

What are the three histological details of salivary glands

acinar cells
myoepithelial cells
ducts

2

What are the acinar cells joined by, surrounding what

tight junctions
central lumen

3

What is the space between the acinar cells called

inter-cellular space

4

What do the tight junctions and intercellular spaces allow what

the passage of water and small ions, but restrict the passage of large molecules

5

The end of the acinar cells that faces the lumen contains what

secretory granules

6

This surrounds the acinar cells

myoepithelial

7

The entire end piece of the acinus is surrounded by what

basal lamina

8

This a pyramidal shape acinar cells resting on a basal lamina with a round nucleus

serous cell

9

True or False
The serous acinar cells contains short, irregular, microvilli

True

10

What kind of characteristics do serous acinar cells exhibit

polarized, protein secreting cells

11

What does the serous acinar cells secrete

many enzymes and glycoproteins

12

What structures are found in a serous acinar cell

rough ER
golgi apparatus
secretory granules
lumen

13

This is a cubodial to columnar cells with an oval nuclei pressed toward the base and is arranged in tubules around a large central lumen

mucous cell

14

What does a mucous cell secrete

mucins

15

What type of staining does the secretory granules undergo

pale staining

16

The shapes of the end pieces of the mucous glands are what in shape

more tubular

17

Why is the cytoplasm of the mucous cells paler staining than that of the serous cells

the mucin is contained within the secretory granules

18

The lemon in the mucous secretory end pieces is more what

larger and more obvious

19

Due to the position of 3 mucous cells topped by 3 serous cells, what is this called; seen during EM scanning

serous demilune

20

When the specimen is prepared with rapid freezing, what is a noticeable difference in regards to the structure

the mucous and serous components appear side by side
also the mucous nuclei is not compressed

21

This surrounds the acini and intercalated discs, lies within the basal lamina, and has multiple processes (surrounding acini)

myoepithelial cell

22

The myoepithelial cell is a specialized epithelial cell that has what

has contractile properties

23

What is the function of the myoepithelial cell

its innervated and functions in expelling saliva into the ductal system

24

What are the three types of ducts associated with salivary glands

intercalated
striated (secretory)
excretory (collecting)

25

This duct empties directly into the oral cavity

excretory

26

What is the flow of saliva through the ducts

intercalated then striated then excretory

27

What differs between the major and minor salivary gland duct system

minor duct arrangement different from major
minor glands have many excretory ducts associated

28

This is the smallest, short duct of which several acini drain into

intercalated duct

29

The cells that make up an intercalated duct look like what

cubodial in shape with a centrally placed nucleus

30

What does the intercalated duct do besides convey saliva

secretes a few antimicrobial proteins

31

This is a longer, more active duct which is the site of reabsorption of sodium and chloride

striated ducts

32

What is the function of started duct absorption

to ensure the saliva reaching the mouth is hypotonic

33

Because reabsorption in the started duct is against the concentration gradient, what must occur

energy is required for which ATP is critical

34

What is the important molecule that started ducts secrete

bicarbonate

35

What is the shape of a started duct cell

columnar
short microvili
numerous infoldings of basolateral membranes; striations
prominent mitochondria
highly polarized

36

Once the started duct cells absorb the sodium and chloride, what happens to it

it gets taken up at the apical end thorough its basal aspect where they pass to capillaries adjacent to striations at the basal end of the cell

37

What is the purpose of excretory ducts

simply carrying the saliva to the oral cavity

38

What become of the shape of the excretory ducts as they get closer to the oral cavity

they become wider

39

What does the single epithelial layer of the excretory change into as it gets cloister to the oral epithelium

psudostratified epithelium; sometime stratified and keratinized

40

Where are excretory ducts often located

in connective tissue

41

What is the shape of the lumen in excretory ducts

irregularly shaped

42

What is the position of the nuclei in excretory ducts

irregularly positioned

43

What kind of cells intermingle/surround excretory ducts

fibroblasts
goblet cells

44

These glands are associated with the taste bud bearing foliate and circumvallate papillae of the posterior tongue

Von Ebner's glands

45

What is a age change that affects 30-60%

general loss of parenchyma

46

True or False
reduced salivary flow does not seem to correlate very strongly with the degree of loss of salivary tissue

True

47

What seems to be the main culprit of reduced salivary flow

prescription medications

48

This viral disease usually affects the parotid gland with painful swelling

mumps

49

This disease/condition is where stones, often in submandibular, obstruct secretion causing painful swelling

sialoliths

50

This disease/condition obstructs secretions from minor glands, causes painful swelling

mucous plugs or trauma

51

True or False
Many viruses replicated and shed into saliva

True; epstein-barr, herpes, etc.

52

The severity of hyposalivation symptoms depends upon what

the degree of salivary loss

53

This is the subjective feeling of dry mouth

xerostomia

54

What is considered a reduced flow rate

less than 0.1ml/min
2/3 reduction from normal levels

55

What additional changes in the oral cavity can result from dry mouth

mucosal changes
enamel erosion
increased caries
difficulty in chewing/swallowing
changes in taste

56

What kind of medications reduce salivary flow

anticholinergic drugs
diuretics
antidepressants
antihistamines
antihypertensives

57

Besides medication, this has a severe effect on salivary flow

head and neck radiation

58

True or False
The reduced salivary flow due to head and neck radiation is both rapid (days) and long lasting

True

59

What is the initial effect on salivary flow due to head/neck radiation

reduced gland function

60

What is the later effect on salivary flow due to head/neck radiation

cell death, primarily of acinar cells

61

True or False
Newer radiation therapies offer no difference in reducing salivary flow

False; the newer therapies more specifically target tumor sites and can spare salivary function

62

What two new therapies are in development to restore salivary flow

stem cell therapies
genetic modification of remaining salivary tissues

63

What are the three ways to manage hyposalivation

frequent dental evaluations and prophylaxis due to prevalence of complications
artificial saliva
salivary stimulants

64

What is a problem with products meant to mimic saliva

must be used frequently
poor patient compliance