EX2; Pulp Flashcards Preview

May14 Oral Histology > EX2; Pulp > Flashcards

Flashcards in EX2; Pulp Deck (75)
Loading flashcards...
1

What is the embryonic origin of the dental pulp

ectoderm
neural crest ectomesenchyme
dental papilla

2

What are the constituents of the dental pulp

cells and cellular elements
blood and lymphatic vessels
extracellular matrix
*not calcified

3

What are the 5 main functions of pulp

inductive
formative
nutritive
protective
defensive/reparative

4

What are the two functions of the protective nature of pulp

sensory; high pressure
barrier; odontoblast junction

5

What are the two functions of the defensive/reparative nature of pulp

immune
formation of new dentin and pulp

6

What is the difference between a young pulp and an old pulp

the young pulp is much larger than the old pulp

7

True or False
Pulp is not normally calcified, but ectopic calcifications are common

True; these are pulp stones, typically most coronal

8

What becomes of calcifications in the pulp as it moves apically

the become diffuse

9

Where can you find diffuse calcifications

in healthy and even un-erupted teeth

10

True or False
Pulp stones cannot be visible radiographically

False; large dense ones can

11

What are the two main histologic organizations in the pulp

odontogenic zone
central (pulp) core

12

What makes up the odontogenic zone

odontoblast layer
cell free zone
cell rich zone

13

What makes up the central (pulp) core

fibroblasts
capillaries/arterioles/venules
nerves (perineural sheath)

14

What are the resident immune system cells found in the pulp

macrophage
lymphocytes
eosinophils
dendritic cells

15

What are the inflammatory immune system cells found in the pulp

plasma cells
mast cells
PMNs

16

These cells in the pulp detect bacterial antigens and are closely associated with the odontoblast layer

dendritic cells

17

These cells serve as a source for replacement of odontoblasts or fibroblasts

stem cells

18

What are the main components of the extracellular matrix of pulp

PGs and associates (GAGs)
glycoproteins
collagen I and III

19

This is involved with collagen fibrillogenesis and water retention of the ECM of pulp

PGs and other associates

20

This is involved in cell adhesion to the ECM

glycoproteins; fibronectin

21

This gives the ECM of pulp tensile strength

collagen I and III

22

True or False;
stem cells are only plentiful during development

False; they are also present in adults

23

What are the clinical implications of adult stem cells in teeth

potential source for repair or correction of genetic defects
tissue-specific stem cell populations well known in regenerating organ (blood, bone, skin)

24

What are the novel concepts of adult stem cells in pulp

extent of plasticity (able to become more/different)
ability to develop complex organized structures

25

What specific type of adult stem cells are derived from dental pulp (bone marrow, etc.)

multipotent

26

Dental pulp stem cells can be induced to form what

odontoblasts
adipocyte
glial-like cells in vitro

27

Dentin-like tissue from the dental pulp stem cells transplanted subcutaneously in immunocompromised mice what occurred

dentin-pulp complex

28

True or False
stem cell niches probably present in multiple location of mature pulp

True

29

These are the 2nd most numerous cell type in the pulp

odontoblast

30

What are the functions of odontoblasts

dentinogenesis
nutrients to dentin
immune