Flashcards in Exam 2: Antibiotics-Quinolones, Metronidazole, Misc, AminoGlycosides Deck (20):
What class of antibiotics is our BIG GUN? Cleans out the garage by BLOWING it up
What is the mechanism of action of Quinolones? Spectrum? Cidal/Static?
Inhibit DNA synthesis during bacterial replication..broad spectrum, bacteriocidal
What is the sub category of Quinolones?
What is the primary antibiotic given to Anthrax exposure?
What is the target for Ciprofloxaxin?
DNA Topoisomerases (busts replication, transcription, and repair. BOOM BITCH)
What is a major oral adverse event of Quniolones?
Qunolones are the first drug to have this type of adverse effect...
CNS! Dizziness, headache, vertigo
What class am I? Medical = to treat resistant organisms
What are the two Quniolones that we need to know?
CiproFloxacin and LevoFloxacin
What class of drugs is antibiotic, amebicide, antiprotozoal Bactericidal, Broad spectrum, and is a Synthetic drug??
Metronidazole: Used to supplement other antibiotics when _________ condition is not responding...Broadens spectrum of kill when used in combination....Not susceptible to ________...Very effective against periodontal pathogens*
KNOW THESE!! What are the 4 adverse effects of MetroNiDazole?
1.Hematopoietic System 2.Metallic Taste 3.Circumoral Paresthesia 4.Oral Ulcerations
Which drug do you ESPECIALLY want to avoid alcohol when using? SO NO EtOH MOUTHWASH!!!! It is a "_______" like reaction.
Metro-ni-dazole.."disulfram" like rxn
What is the mechanism of action of Vancomycin?
Inhibits bacterial cell wall synthesis (diff from penicillin tho)
Vancomycin (Vancocin) “________” antibiotic, Inhibits _______ synthesis, but with a different mechanism than the penicillins...Used for ______ staph infections, strep infections, enterococcal infections...Used to treat antibiotic-induced pseudomembranous colitis caused by _____.
“miscellaneous”...bacterial cell wall..resistant...C/ Diff
Who am I? Was considered one of the last lines of antibiotic defense...Now, many cases of vancomycin-resistant bacteria: especially enterococci...Prompted the development of new classes of antibiotics in U.S.
What class am I? These are products of actinomycetes (soil bacteria) or semi- synthetic derivatives of the natural products.
What is the mechanism of action for Aminoglycosides?
Binds to 30s ribosome
What word does aminoglycosides end in?