Exam 2: Antibiotics-Quinolones, Metronidazole, Misc, AminoGlycosides Flashcards Preview

Pharmacology > Exam 2: Antibiotics-Quinolones, Metronidazole, Misc, AminoGlycosides > Flashcards

Flashcards in Exam 2: Antibiotics-Quinolones, Metronidazole, Misc, AminoGlycosides Deck (20):
1

What class of antibiotics is our BIG GUN? Cleans out the garage by BLOWING it up

Quniolones

2

What is the mechanism of action of Quinolones? Spectrum? Cidal/Static?

Inhibit DNA synthesis during bacterial replication..broad spectrum, bacteriocidal

3

What is the sub category of Quinolones?

FluoroQuniolones

4

What is the primary antibiotic given to Anthrax exposure?

CiproFloxacin

5

What is the target for Ciprofloxaxin?

DNA Topoisomerases (busts replication, transcription, and repair. BOOM BITCH)

6

What is a major oral adverse event of Quniolones?

Xerostomia!

7

Qunolones are the first drug to have this type of adverse effect...

CNS! Dizziness, headache, vertigo

8

What class am I? Medical = to treat resistant organisms

Quniolones

9

What are the two Quniolones that we need to know?

CiproFloxacin and LevoFloxacin

10

What class of drugs is antibiotic, amebicide, antiprotozoal Bactericidal, Broad spectrum, and is a Synthetic drug??

Metro-Ni-Da-Zole

11

Metronidazole: Used to supplement other antibiotics when _________ condition is not responding...Broadens spectrum of kill when used in combination....Not susceptible to ________...Very effective against periodontal pathogens*

periodontal...penicllinase

12

KNOW THESE!! What are the 4 adverse effects of MetroNiDazole?

1.Hematopoietic System 2.Metallic Taste 3.Circumoral Paresthesia 4.Oral Ulcerations

13

Which drug do you ESPECIALLY want to avoid alcohol when using? SO NO EtOH MOUTHWASH!!!! It is a "_______" like reaction.

Metro-ni-dazole.."disulfram" like rxn

14

What is the mechanism of action of Vancomycin?

Inhibits bacterial cell wall synthesis (diff from penicillin tho)

15

Vancomycin (Vancocin) “________” antibiotic, Inhibits _______ synthesis, but with a different mechanism than the penicillins...Used for ______ staph infections, strep infections, enterococcal infections...Used to treat antibiotic-induced pseudomembranous colitis caused by _____.



“miscellaneous”...bacterial cell wall..resistant...C/ Diff

16

Who am I? Was considered one of the last lines of antibiotic defense...Now, many cases of vancomycin-resistant bacteria: especially enterococci...Prompted the development of new classes of antibiotics in U.S.

Vancomycin

17

What class am I? These are products of actinomycetes (soil bacteria) or semi- synthetic derivatives of the natural products.

Aminoglycosides

18

What is the mechanism of action for Aminoglycosides?

Binds to 30s ribosome

19

What word does aminoglycosides end in?

mycin....dont confuse

20

What is the main side effect of aminoglycosides?

Ototoxic-hearing loss