Exam 3 - Acid Base Balance Flashcards

(50 cards)

1
Q

what is an acid

A

substances that release hydrogen ions when dissolved in fluid and increase amount of free H

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2
Q

what is a base

A

binds free hydrogen ions in solution and lowers amount of free H

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3
Q

what is a buffer

A

tries to keep pH at normal levels - can bind hydrogen or release

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4
Q

what is the most common base in the human body

A

HCO3 (bicarbonate)

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5
Q

what is the most common acid in the human body

A

H2CO3 (carbonic acid)

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6
Q

what is the ratio of H2CO3 and HCO3 in the human body

A

1 H2CO3 : 20 HCO3

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7
Q

what does carbohydrate make as a waste product in normal metabolism

A

carbon dioxide

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8
Q

what does protein make as a waste product in normal metabolism

A

sulfuric acid

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9
Q

what does fat make as a waste product in normal metabolism

A

ketoacids

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10
Q

what are the two buffers? and where are they active?

A

phosphate (ICF) and bicarb (both ECF and ICF)

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11
Q

what are the two types of ECF protein buffers?

A

albumin and globulins

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12
Q

what is the ICF protein buffers?

A

hemoglobin

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13
Q

what are the kidneys defense for regulation

A

form ammonium, form acids or movement of bicarbonate

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14
Q

what happens in acidosis

A

excess amount of hydrogen ions (pH below 7.35)

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15
Q

what is actual acidosis

A

overproduction(release of H) or under elimination of acids (retention of H)

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16
Q

what is relative acidosis

A

amount of acids do not increase, amount of strength of bases decrease

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17
Q

where do the first manifestations occur for acidosis?

A

musculoskeletal, cardiac, respiratory, and central nervous system

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18
Q
what happens when there is a
overproduction of hydrogen ions
under elimination of hydrogen ions
underproduction of bicarbonate ions
and over elimination of bicarbonate ions?
A

metabolic acidosis

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19
Q

how does overproduction of hydrogen ions cause metabolic acidosis

A

excessive breakdown of fatty acids
anaerobic glucose breakdown (lactic acidosis)
excessive intake of acids

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20
Q

how is respiratory acidosis caused?

A

retention of co2

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21
Q

what are the four conditions that may cause respiratory acidosis?

A

respiratory depression
inadequate chest expansion
airway obstruction
reduced alveolar-capillary diffusion

22
Q

interventions of metabolic acidosis?

A

drugs and fluid

23
Q

interventions of respiratory acidosis?

A

drug therapy (bronchodilator, anti-inflammatory, mucolytics)
oxygen therapy
ventilation therapy
preventing complications

24
Q

what is alkalosis

A

a decrease in hydrogen ions

25
what are the problems most caused by alkalosis?
neuromuscular, cardiac, nervous
26
what causes metabolic alkalosis?
excessive intake of carbonates, acetates and citrates | disease process and medical therapy
27
what causes resiratory alkalosis?
excessive loss of co2
28
what are the numbers for the pH of pCO2
35 below is alkalotic | 45 and above is acidotic
29
what are the numbers for the pH of HCO3
22 and below is acidotic | 26 and above is alkalotic
30
what is the mnemonic for metabolic and respiratory?
Respiratory Opposite Metabolic Equal
31
How do you determine the origin of the imbalance?
which one matches the same acid base status as the pH
32
how do you determine compensation?
present if opposite direction | absent if one component abnormal and other normal
33
what is partial compensation?
when pH remains outside the normal range
34
respiratory acidosis is also known as
hypoventilation
35
respiratory alkalosis is also known as
hyperventilation
36
``` tachycardia dysrhythmias anxiety irritability confusion coma ```
respiratory acidosis
37
``` tachypnea palpitations chest pain dysrhythmias anxiety tetany convulsions tingling/numbness ```
respiratory alkalosis
38
``` bradycardia tachypnea hypotension dysrhythmias fatigue weakness lethargy confusion anorexia nausea vomiting diarrhea ```
metabolic acidosis
39
``` tachycardia hypotension dysrhytmnias numbness tingling tetany muscle weakness hyporeflexia confusion convulsions polyuria polydipsia ```
metabolic alkalosis
40
what is metabolic alkalosis
excessive loss of metabolic acids | bicarb increases
41
how does the respiratory system compensate for metabolic alkalosis
slow shallow breaths co2 retained paCO2 increase
42
what is metabolic acidosis
bicarbonate loss - too much H+ produced
43
what is respiratory alkalosis
carbonic levels fall and pH rises | more than normal co2 is exhaled
44
how does the respiratory alkalosis get compensated
kidneys excrete bicarbonate or hyperventilation stops
45
what causes respiratory alkalosis
hyperventilation fever aspirin toxication
46
what is respiratory acidosis
carbonic levels increase and pH decreases | co2 retention
47
how does respiratory acidosis get compensated
kidneys retain bicarbonate and eliminate hydrogen
48
what lung diseases causes respiratory acidosis
``` asthma copd penumonia pulmonary edema respiratory muscle wall paralysis ```
49
what CNS depression causes respiratory acidosis
anesthesia narcotic overdose head injury
50
what is the main treatment for respiratory acidosis
increase ventilation to blow off co2!!