Exam 3: Caffeine Flashcards
How many Americans use caffeine?
90% of Americans
Caffeine is the most common _____?
Psychostimulant
How does caffeine get absorbed?
Through oral absorption like food, pills, drinks
Describe the distribution of caffeine?
Caffeine will peak at ~ 40 minutes and complete absorption will happen over 90 minutes
It is both lipid and water-soluble and crosses the blood-brain barrier
Where does metabolism occur for Caffeine?
The Liver
How many metabolites does caffeine have?
3 (theophylline, theobromine, and paraxanthine)
How is coffee eliminated from the body?
It is eliminated by the kidneys and excreted in urine
Outline the Half-life of caffeine:
~ 3 - 10 hours in adults
Different circumstances will cause the half-life to increase
- Birth control will cause the half-life to double
-the half-life is extended when taking SSRIs
What is the Half-life of caffeine in a human adult:
~ 3 - 10 hours in adults
What are some of the effects that caffeine will induce?
Increased Heart Rate
Increased Breathing rate
Increased attention, alertness, and energy
Reduced appetite
Blood vessel contraction
Sleep disturbances
What can occur when caffeine is taken in high doses?
Caffeinism
What is an effect that do not become tolerant?
Cardiovascular activity
What is the main sign of withdraw from caffeine?
Headache
What are some other symptoms of caffeine withdraw
Drowsiness, fatigue, depression, anxiety, irritability, pain, and craving
