Exam 6- Lymphoepithelial Sialadenitis Flashcards
(26 cards)
PEN AND PAPER: What are the 4 examples given for Lymphoepithelial sialadenitis?
1.MyoEpithelial Sialadenitis 2.Benign LymphoEpithelial Lesion 3.Mik-UL-icz disease 4.Sjogrens Syndrome
LymphoEpithelial sialadenitis is a ________ condition of salivary glands producing asymptomatic ______
NON-neoplastic….SWELLING
Which sex is more affected by lymphoepithelial sialadenitis? What age range?
females 3:1…4-7th decade (aunt sue and her sjogrens)
What gland does 90% of lymphoepithelial sialadenitis affect? Occasionally which other gland??
parotid..submandibular
Lymphoepithelial sialadenitis is not synonymous with _________ but most patients with this condition have lymphoepithelial sialadenitis…chew on that one…
Sjogrens Syndrome
The histopathology of lymphoepithelial sialadenitis shows inflammatory/immune infiltrates that REPLACE salivary acini and residual ducts showing squamous ________
METAplasia
Sjogrens-________ disease mainly affects ______ and ______ glands
autoimmune…salivary and lacrimal
What % of sjogrens syndrome affects FEMALES?
80-90%
What is Primary sjogrens mean?
no other autoimmune disease
What does secondary sjogrens mean?
associated with other autoimmune diseases (RA, SLE)
How many of the 6 diagnostic tests have to be positive for there to be a diagnosis of sjogrens?
4/6 (1.dry eye 2.dry mouth 3.saliva flow test 4.ocular test 5.biopsy 6.blood test
What is the GOLD standard for diagnosing sjogrens syndrome?
Oral Labial Biopsy
WHAT IS THE BIGGEST thing we need to MONITOR for patients with Sjogrens?
40x increased risk for LYMPHOMA! (MALT-marginal zone lymphoma)
What is a Multi-system granulomatous disorder of unknown cause?
SAR-COID-OSIS
SarCoidOsis is a Multi-system __________ disorder of UNKNOWN cause
granulomatous
What are the demographics for SarCoidOsis? (age,race,sex)
20-40 y/o, black, female
SarCoidOsis Affects lungs, lymph nodes, skin, eyes and WHAT?
salivary glands
What % of sarcoidosis is ASYMPTOMATIC?
20%
SarCoidOsis is diagnosed by clinical findings, _____ radiographs (bilateral hilar lymphadenopathy), biopsy, ↑ serum _____ (Angiotensin converting enzyme)
chest…ACE
What two syndromes are related to SarCoidOsis?
Lofgren’s syndrome and Heer-fordT’s syndrome
What is the distunishing characteristic in Lofgren’s syndrome?
Bilateral Hilar Lymph-Adenom-Pathy
What is the distinguishing characteristic in HeerFordT’s syndrome?
parotid enlargement (facial paralysis)
What is another name for FREY syndrome?
AuriculoTemporal Syndrome
WHEN do flushing, sweating, warmth in preauricular and temporal skin occur during FREY syndrome?
while CHEWING!
