Exam 6-LCH, ORN, TBC

Question 1

What is the freaking CLASSIC sign of Langerhan’s Cell Histocytosis??

Answer 1

FLOATING TEETH

Question 2

What are the two synonyms for Langerhan’s cell histocytosis?

Answer 2

Langerhan’s Cell Disease and HistioCytosis X

Question 3

What age group is most affected by Langerhan’s cell histocytosis? 50% of patients are under WHAT AGE??

Answer 3

young patients (rare in adults)…50% under age 10

Question 4

What two types of tissues are affected by Langerhan’s Cell Histocytosis?

Answer 4

bone and soft tissue

Question 5

What are the three flavors of Langerhan’s cell Histocytosis? AND, PLEASE rank them in order of worst prognosis to best?

Answer 5

1.Letter-er-SI-WE Disease 2.Hand-SCHULER-Christian Disease 3.EiosinophiLIC Granuloma

Question 6

Which flavor of Langerhan’s cell Histocytosis is also known as Acute Disseminated Langerhans Cell Histiocytosis?

Answer 6

Letterer-SI-WE disease

Question 7

What age range is most affected by Letterer-SI-WE disease?

Answer 7

infants under 2 years

Question 8

Which flavor of Langerhan’s cell Histocytosis involves multiple organs and sites, has an AGGRESIVE disease course and is invariably FATAL?

Answer 8

Letterer-SI-WE Disease

Question 9

Letterer-SI-WE disease is also known as:

Answer 9

ACUTE Disseminated Langerhans Cell Histiocytosis

Question 10

Hand-Schuler-Christian Disease is also known as:

Answer 10

CHRONIC Disseminated Langerhans Cell Histiocytosis

Question 11

Chronic Disseminated Langerhans Cell Histiocytosis is also known as:

Answer 11

Hand-Schuler-Christian Disease

Question 12

What is the typical age range for kids with Hand-Schuler-Christian disease?

Answer 12

3-10 years old

Question 13

Which flavor of Langerhan’s cell Histocytosis has multiple sites of involvement, Slower progression with better prognosis?

Answer 13

hand-schuler-christian disease

Question 14

Which flavor of Langerhan’s cell Histocytosis is also known as CHRONIC LOCALIZED Langerhans Cell Histiocytosis?

Answer 14

Eiosinophillic granuloma

Question 15

Which age group is primarily affected by eiosinophillic granuloma?

Answer 15

teenagers and young adults

Question 16

What is the main tissue type affected by eiosinophillic granuloma?

Answer 16

bone

Question 17

What is the prognosis of eiosinophillic granuloma?

Answer 17

generally good

Question 18

Radiographic features of Langerhans Cell Histiocytosis: Radio______, singular/mulitple?, Often ill-defined; BUT may be ________

Answer 18

lucent…multiple, circumscribed

Question 19

Radiographic features of Langerhans Cell Histiocytosis: again, what is the CLASSIC radiographic sign???

Answer 19

“teeth floating in air”

Question 20

Radiographic features of Langerhans Cell Histiocytosis: The teeth are “floating in air” BUT they are NOT _______ by the lesion

Answer 20

displaced

Question 21

Radiographic features of Langerhans Cell Histiocytosis: what anatomical feature is typically lost (contributing to the “teeth floating in air” appearance)

Answer 21

loss of lamina dura

Question 22

What the heck ARE Langerhans Cells?? ________ cells involved in ______ processing

Answer 22

immune cells….antigen processing

Question 23

What are the two treatments for Langerhans Cell Histocytosis?

Answer 23

Curettage and/or low dose radiation therapy

Question 24

Freggin slam dunk: which condtion is always seen in an area of radiation therapy?

Answer 24

OsteoRadioNecrosis

Question 25

When seeing osteoradionecrosis of the jaw, the patient will give a history of prior cancer, usually ________

Answer 25

squamous cell carcinoma

Question 26

WHY does ORN happen? Radiation permanently damages the bone by destroying ________ in the area

Answer 26

blood vessles

Question 27

What is one of the major complications from OSN? Increases susceptibility to _______

Answer 27

INFECTION

Question 28

In ORN, The higher the ___________, the GREATER the risk

Answer 28

radiation dose

Question 29

In ORN, Severe ______ is INVARIABLY present

Answer 29

PAIN

Question 30

In ORN the lesion will NOT heal without _________

Answer 30

SURGICAL INTERVENTION

Question 31

What is the MOST IMPORTANT treatment for ORN??

Answer 31

PREVENTION

Question 32

For PRE-treating before radiation therapy, Extract ALL questionable teeth that will be in the ______ of radiation

Answer 32

field of radiation

Question 33

Once ORN is already present, treat by ________ regimen often used but efficacy questioned, ________ of dead bone to viable bleeding bone, _______ closure over the surgical site

Answer 33

Hyperbaric oxygen....resection...Soft tissue

Question 34

A traumatic bone cyst is also known as a _______

Answer 34

simple bone cyst

Question 35

Traumatic Bone Cyst (Simple bone cyst)--Clinical features: Radio_____ lesion, often ______ up between tooth roots

Answer 35

lucent...scallops

Question 36

Traumatic Bone Cyst (Simple bone cyst)--Clinical features: typically affects young patients who are active...so usually in their ____'s

Answer 36

20's

Question 37

Traumatic Bone Cyst (Simple bone cyst)--Clinical features: they are __________, so they are often discovered by _______

Answer 37

Asymptomatic...radiographic exam

Question 38

Traumatic Bone Cyst (Simple bone cyst) Clinical features: which arch is affected? (almost EXLUSIVELY)

Answer 38

mandible

Question 39

Traumatic Bone Cyst (Simple bone cyst) Clinical features: are they expansile or non-expansile?

Answer 39

since there are no symptoms....non-expansile

Question 40

Traumatic Bone Cyst (Simple bone cyst) Clinical features: WHAT is discovered in the bone?? little/no ______ is recovered, or they contain _____ tinged fluid

Answer 40

an empty "hole"...tissue...blood

Question 41

WHICH pathology has characteristic "scalloping" up in between tooth roots?

Answer 41

Traumatic Bone Cyst (Simple bone cyst)

Question 42

How is a Traumatic Bone Cyst (simple bone cyst) typially treated?

Answer 42

STIMULATE BLEEDING and CURETTE