Exam 2-Non-Neoplastic Proliferations Flashcards Preview

ORAL PATHOLOGY! > Exam 2-Non-Neoplastic Proliferations > Flashcards

Flashcards in Exam 2-Non-Neoplastic Proliferations Deck (81):
1

Patients commonly present with swelling (_________). This can be the result of _________, a ______ lesion or a ________ lesion (either benign or malignant).

TUM--E--faction...inflammation... reactive.... neoplastic

2

_______ tumors are usually the result of hyperplasia which is due to an increase in the number of normal cells

REACTIVE

3

Reactive tumors are usually the result of _________ which is due to an increase in the number of normal cells

hyperplasia

4

Reactive tumors are usually the result of hyperplasia which is due to an increase in the number of ______ cells

NORMAL

5

While reactive tumors can become quite large, they are not considered to have “unlimited _________” like neoplasms

growth potential

6

reactive tumors are thought to be the result of the body’s reaction to a stimulus (often ______ irritation)

physical

7

Reactive lesions constitute about ___% of all lesions biopsied in a dental office.

20%

8

________ lesions constitute about 20% of all lesions biopsied in a dental office.

REACTIVE

9

_______: Hyperplasia of fibrous connective tissue

fibroma

10

WHAT IS THE MOST COMMON TUMOR OF THE ORAL MUCOSA?

FIBROMA!!

11

What am I describing?? usually sessile, smooth surfaced, normal color, asymptomatic

Fibroma

12

Where are fibroma's most often found?

Cheek, but can be found everywhere

13

What is the variant that you DON'T want to confuse with a giant cell granuloma?

Giant Cell Fibroma

14

What can a Giant Cell Fibroma be sometimes confused with in name? WHAT ABOUT CLINICALLY??

A Giant cell granuloma...Clincially: Papilloma

15

________: “papillary” tumor of fibrous connective tissue containing plump, stellate and often bi or trinucleated fibroblasts

Giant Cell Fibroma!

16

Which age group is most susceptible to Giant Cell fibromas?

Children

17

What are the two most common areas to find a Giant Cell Fibroma?

1. Gingiva 2.Tongue

18

What is a reactive, fibroblastic lesion of PDL?

Peripheral Odontogenic (Ossifying) Fibroma

19

What is the most common age range for a Peripheral Odontogenic (Ossifying) Fibroma?

10-30 years old

20

Where is the ONLY place a Peripheral odontogenic (ossifying) fibroma occurs?

The gingiva (PDL)

21

What are the symptoms associated with a Peripheral Odontogenic (Ossifying) Fibroma?

HAHA GOT YA! NONE...Asymptomatic

22

What could I be describing??: pedunculated or sessile mass ± red ± ulceration

Peripheral Odontogenic (Ossifying) Fibroma

23

What am I describing?: Histology: Cellular fibroblastic lesion with bone and/or cementum and/or dystrophic calcification

Peripheral Odontogenic (Ossifying) fibroma

24

What is the treatment for a Peripheral Odontogenic (Ossifying) Fibroma?

Excision, including superficial PDL

25

WHICH REACTIVE GINGIVAL LESION HAS HIGHEST RECURRENCE RATE? What is the rate?

Peripheral Odontogenic (Ossifying) Fibroma...15-20% recurrence rate

26

What is another name for Inflammatory Fibrous Hyperplasia?

Epulis Fissuratum

27

What are reactive folds of hyperplastic fibrous connective tissue along border of ill-fitting, over extend denture (2 names please)

1.Inflammatory Fibrous Hyperplasia 2.Epulis Fissuratum

28

What is the histology of an epulis fissuratum (inflammatory fibrous hyperplasia)?

lol...fibrous hyperplasia and inflammation (I wonder how it got its name??)

29

What is the treatment for Inflammatory fibrous hyperplasia (aka. epilus fissuratum)

excision and reline (or remake) the denture

30

What is another name for Inflammatory Papillary Hyperplasia?

Papillamatosis

31

What is classified as a hyperplastic response of palatal mucosa to ill-fitting denture

Inflammatory Papillary Hyperplasia (papillamatosis)

32

What is the fancy term for the histology of a Inflammatory Papillary Hyperplasia?

Pseudo-Epithel-io-matous Hyperplasia (PEH)

33

What is the treatment for Inflammatory Papillary Hyperplasia?

Excise, remake/reline

34

What is a Tumor of well vascularized fibrous connective tissue containing numerous multinucleated giant cells?

Peripheral Giant Cell Granuloma

35

What is the most common site for a Peripheral Giant Cell Granuloma?

the anterior gingiva

36

What is the typical age for the occurrence of a peripheral giant cell granuloma? What are the typical symptoms?

any age, asymptomatic

37

Which type of lesion can be a usually reddish-brown-purple pedunculated or sessile mass

Peripheral Giant Cell Granuloma

38

Who is affected more by peripheral giant cell granulomas: males or females?

females 2:1!!

39

Which type of lesion may produce cupping resorption of underlying bone?

Peripheral Giant Cell Granuloma

40

Treatment of a Peripheral Giant Cell Granuloma: Excision and removal of irritants, may DO WHAT?

RECUR!

41

Why is a pyogenic granuloma a misnomer?

because its not a pus producing lesion...its a reactive lesion made of granulation tissue

42

What lesion is reddish, ulcerated pedunculated or sessile mass?

Pyogenic Granuloma

43

What are the most common age ranges for a Pyogenic Granuloma and where is the most common site for one? WHAT ARE THE SYMPTOMS?

20-40 years old and on the gingiva...Asymptomatic but may bleed easily (I THINK I HAVE ONE OF THESE!!)

44

What lesion has the nickname of "pregnancy tumor"?

Pyogenic Granuloma

45

What is a pyogenic granuloma called in an extortion socket?

Epilus Granulomatosa

46

This is the histology of WHAT type of non-neoplastic proliferation???: Hyperplastic granulation tissue, fibroblasts with delicate collagen, endothelial cells + capillaries and dilated larger vessels

Pyo-genic Granuloma

47

Can a pyogenic granuloma recur if it is excised?

Yep!

48

What is another name for a gum boil?

"Parulis"

49

Hmmm...WTF am I talkin' bout? Can occur anywhere but on gingiva, it represents draining from a source of odontogenic infection of either pulpal or periodontal origin pus (purulence, suppuration) = bacterial infection

A Parulis/Gum Boil

50

Holy shit, what is the 5 word name for this indication: Localized hyperplasia presumably from externalized sulcular epithelium on gingiva....(typically in JUVENILES!)

Localized juvenile spongiotic gingival hyperplasia

51

Localized juvenile spongiotic gingival hyperplasia: ALMOST EXCLUSIVELY in what age range and what sex?

10-30 y/o and 2:1 female

52

Localized juvenile spongiotic gingival hyperplasia: almost all ________ gingiva, and which arch is more likely?

anterior....maxillary arch

53

Localized juvenile spongiotic gingival hyperplasia: WHAT COLOR?... often _______ gingival lesions

RED.... papillary

54

WHO AM I? (I don't know) Papillary proliferation of inflamed epithelium with intercellular edema (spongiosis)

Localized juvenile spongiotic gingival hyperplasia:

55

What is an Overgrowth of blood vessels ?

Hemangioma

56

(________– localized overgrowth of tissues native to the part, often developmental)

hamartoma

57

HEMANGEOMA is a rapid proliferation of WHAT TYPE OF cells at birth or shortly thereafter, characteristically INVOLUTE (whatever the f that means)

ENDOTHELIAL

58

**What is the most common tumor of infancy?!?

Hemangioma (5-10%) incidence

59

What sex is more likely to have a HE-MAN-geoma? What % of these are in the Head and Neck?

Females (3:1)...60% are Head and Neck

60

When is the MOST likely age range for a HE-MAN-gioma to develop? They are 90% developed at what age?

0-5 years...90% by age 10

61

Is a He-Man-gioma congenital?

RARELY congenital!

62

What is a reddish to purple mass lesions that tend to blanch with pressure?

Hemangioma

63

What is UNIQUE about an ORAL hemangioma?

they develop later in life and don't involute

64

Which NON-Neoplastic Proliferation can occur in BONE, often multilocular or soap bubble appearance (why you aspirate before bone biopsy)???

Hemangioma

65

Which non-neoplastic proliferation histologically has Endothelial cell proliferation with formation of small capillaries (capillary) or larger dilated vascular spaces (cavernous)?

Hemangioma

66

What non-neoplastic proliferation is treated via these methods: Natural history is INVOLUTION laser pulse, excision, sclerosing agents, steroids both intralesional and systemic, propranolol

Hemangioma

67

WTF is this?? Nonhereditary developmental, congenital condition characterized by vascular proliferation of brain and face usually along distribution of ophthalmic branch of the trigeminal nerve??

STURGE-WEBER ANGIO-MAT-OSIS

68

What is the scientific name for Sturge-Weber Angiomatosis? (think of its location!!)

Encehpalo-Trigeminal Angiomatosis

69

Is Sturge-Weber hereditary?

Non-hereditary

70

Is Sturge-Weber congentical?

Yes, it is congenital

71

THIS IS....AWESOME!!!! Sturge-Weber and port wine stains are due to somatic activation mutation in _____ which encodes Gαq, a member of the q class of ________ alpha subunits that mediates signals between ________–coupled receptors and downstream effectors. The difference is when and where the mutation occurs

GNAQ....G-Protein..G-PROTEIN

72

Sturge-Weber: Large WHAT COLOR lesions –identical clinically to ________ stains, (IPSILATERAL or CONTRALATERAL) oral mucosal involvement common leptomingeal angiomas of cerebral cortex

Purplish...port-wine...IPSILATERAL

73

You better not get this shiz wrong: What is a developmental overgrowth of lymphatic vessels?

Lymphangioma

74

Where are the most common regions for lymphangioma and what age are they most common in?

head and neck....0-5 years

75

Where is the most common place for a lymphangioma in the mouth?

on the TONGUE!!

76

What type of tongue pathology can be the result of lymphangioma

MACROglossia

77

A superficial lymphangioma is likely to have a _____ surface with translucent vesicles.

pebbly

78

Are deeper lymphangiomas of the tongue more concentrated or more diffuse?

more diffuse

79

What is the VARIANT of a Lymphangioma that infiltrates and becomes VERY large (↑ neck)?

Cystic Hy-GRO-ma

80

This is the Histology of WHAT? Proliferation of thin walled lymphatic vessels capillary sized, Dilated (cavernous) or cystically dilated (cystic hygroma)

Lymphangioma

81

This is the treatment for WHICH non-neoplastic proliferation: Lesions don’t involute, Excision, Deeper ones often recur, Sclerosing agents

Lymphangioma