Exam II Review (F. tubes, ovary, uterus, prego stuff) Flashcards

(41 cards)

1
Q

What is the term used for endometrial tissue that forms tumor-like nodules outside the uterus?

A

Endometriosis

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2
Q

Where are the three MOST COMMON locations for endometriosis?

A

Ovary, Fallopian Tube, and the Pelvic Peritoneum (also pelvis, umbilicus, appendix, colon)

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3
Q

What two groups of women are most likely to develop endometriosis?

A

1.”women of reproductive life” haha no shit. 30’s and 40’s….2.Women in higher socio-economic grps who marry late in life

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4
Q

The _________ theory: the endometrial tissue is ________ during normal menstruation and, instead of entering the vagina, it is transferred upstream where it enters the _________ through the fallopian tubes.

A

regurgitation…..regurgitating….abdominal cavity

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5
Q

Endometreosis: The glands implant on the ______ of the ovary or the peritoneum, forming typical ________ nodules or plaques.

A

serosa….red-brown

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6
Q

What are the two names for benign tumors originating from the smooth muscle cells of the myometrium.

A

Leio-my-omas (leio-smooth myo-muscle)…..FIBROIDS

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7
Q

What are the 3 types of fibroids? (leiomyomas)

A

1.Intramural (in the myometrium) 2.Subserosal (beneath the covering serosa of the uterus) 3.Submucosa (protrude into the endometrial cavity)

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8
Q

What are most common in the 3rd and 4th decades and more common in blacks?

A

Leiomyomas (fibroids)

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9
Q

When do leiomyomas/fibriods occur?

A

during reproductive life, 30’s and 40’s

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10
Q

What is the MOST COMMON UTERINE TUMOR? What % of women of reproductive age have them?

A

Leiomyoma/fibroid….20%

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11
Q

What % of Leiomyomas are benign?

A

98% benign… 2% malignant <—nice math dawg!

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12
Q

Grossly, they are sharply circumscribed, unencapsulated white-tan whorled masses on cut section.

A

leiomyoma/fibroid

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13
Q

What are the 4 risk factors for endometrial carcinoma?

A

1.Exogenous Estrogen 2.Estrogen secreting tumors 3.obese (and therefore synthesize estrogen from fat) 4.Nulliparous/Early menarche/late menopause (more estrogen exposure)

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14
Q

What is the most common MALIGNANT tumor of the female UroGenital Tract? What % of all GYN malignancies?

A

Endometrial Adenocarcinoma…50% of all GYN malignancies

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15
Q

What are the three types of endometrial hyperplasias and what are the % of it turning into an adenocarcinoma?

A

1.Simple hyperplasia (minimal glandular complexity)- 1% 2.Complex hyperplasia(multilayering of the glands)- 3% 3.Atypical hyperplasia(complexity to the glands with crowding and there is cytologic atypia)- 25%

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16
Q

What TYPE of cancer is Endometrial Adenocarcinoma?

A

Glandular Cancer

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17
Q

Where does Endometrial Adenocarcinoma originate?

A

Arises from the epithelial cells lining the endometrial glands

18
Q

What are the 3 treatments for endometrial adenocarcinoma?

A

1.historectomy (w or w/o ovaries…TAH-BSO) (lymph resection possible too) 2.Radiation in advanced cases 3. Chemo(inoperable cases)

19
Q

What is the most common clinical sign for a woman with endometrial adenocarcinoma?

A

Vaginal bleeding between two menstruations or prolonged menstral bleeding…ESPECIALLY post menopausal women

20
Q

What is the age range for endometrial adenocarcinoma?

A

older women, rare before 35

21
Q

Ectopic Pregnancy: Clinically, there is onset of severe _______ pain with rupture and the possibility of _______.

A

abdominal…..hypovolemic shock

22
Q

Would you get a positive pregnancy test during an ectopic pregnancy?

23
Q

Ectopic Pregnancy: Aspiration of fresh blood from ___________ (posterior fornix) denotes rupture.

A

the pouch of Douglas

24
Q

An ________ biopsy is helpful in diagnosis.

25
The absence of _________ is consistent with an ectopic pregnancy. Why?
chorionic villi (placental tissue)....the villi are in the tube.
26
Ectopic Pregnancy: All the biopsy will show is a _______ reaction of the endometrium.
decidual
27
In an Ectopic Pregancy a ultra sound will show _______ of the fallopian tube.
dilation
28
Rupture due to an ectopic pregnancy is a medical emergency since 1 in ____ of these patients dies before hemorrhage can be controlled. About how long is the pregnancy before a hemmorage can occur?
1 in 400...2-6 wks.
29
Implantation of the fetus in any other site than the normal uterine location, most common places are the _____, ________, and _________ (___%).
ovary, abdominal cavity, and the fallopian tubes (95%)!!
30
An ectopic pregnancy occurs within 1 and every _____ pregnancies!
1 in 150!! pretty common!
31
What are the 4 main causes of an Ectopic Pregnancy?
1.Chronic Salpingitis (caused by P.I.D.-Ghonorrhea & Chlamydia)..........Adhesions caused by 2.endometreosis 3.surgeries 4.leiomyomas
32
What are the 2 main consequences of a Pelvic Inflammatory Disease? What are the two causative agents again?!?
1.Ectopic Pregnancy 2. Infertility... 1. Neisseria gonorrhoeae & 2. Chlamydia trachomatis
33
What are the 3 GYN ADENOCARCINOMAS?
1. Fallopian Tube 2. Endometrial (endocervix) 3.Ovarian:Surface Epithelium
34
What the 3 GYN SQUAMOUS CELL CARCINOMAS?
1.Vulva 2. Vagina 3.Cervix (exocervix)
35
What are the 4 types of tumors derived from OVARIAN SURFACE EPITHELIUM? Which two are cystic? Which two are more solid?
1.Serous 2.Mucinous (both more cystic) 3.Brenner 4. Endometroid (both more solid)
36
What are the 4 most common Germ cell tumors?
1. Benign Cystic Tetroma 2.Dysgerminoma 3.Endometiral Sinus Tumor 4.Choriocarcinoma
37
What are the 3 types of sex cord tumors?
1.Thecoma 2. Granulosa cell 3.Sertoli-leydig
38
What is the antibody to SURFACE EPITHELIAL ovarian cancer detected in the serum in 1/2 of the epithelial tumors? How much has the malignancy spread at this point?
CA-125....90%
39
What tumor secretes estrogens?
Thecomas (Sex Cord Tumors of the Ovary)
40
Which tumor secretes androgens?
Sertoli-leydig Stromal Tumors (sex cord tumors of the ovary)
41
Which ovarian tumor secretes CA-125?
about 1/2 of surface epithelial tumors of the ovary. (about 90% of the malignancy has spread at this point)